Klex, Fs. Lasik And Transprk In Correcting Myopia
Published 2025 - 43rd Congress of the ESCRS
Reference: FP26.11 | Type: Free paper | DOI: 10.82333/1nya-ra11
Authors: Chetan Vilas Ahiwalay* 1 , Bonnie An Henderson 2 , Kimaya Chavan 3
1Cataract services ,SweeMyra Netralaya,Thane,India, 2Cataract services ,Tufts University school of Medicine,Boston,United States, 3Cataract services ,Chavan Hospital,Mumbai,India
Purpose
To evaluate efficacy, safety and predictability of KLex, Fs. LASIK and TransPRK in correcting myopia and myopic astigmatism.
Setting
Refractive surgery department in University Eye Hospital Svjetlost, Zagreb, Croatia
Methods
A prospective randomized study was conducted on 240 eyes evenly distributed in 3 groups according to surgical correction methods: TransepithelialPRK (SmartSURFACE), FS. LASIK and KLEX (SmartSIGHT) using Schwinf ATOS for flap and lenticule formation and Schwind AMARIS 1050S for excimer laser ablation. Comparison of refractive results, corneal opacity/haze and subbasal nerve plexus regeneration (nerve fiber length - CNFL, total branch density - CTBD) was observed at 1 week, 1, 3 and 6 months after surgery.
Results
In first week and first month postoperativelly there was a statistically signifficant difference in UDVA, sphere and cylinder correction between the groups (p< 0,0001) but at 3 and 6 months follow up no diference was observed (p > 0.05). At the end of the follow up 91-94% of monitored eyes was within 0.25-0.5 SE, and 100% of eyes were within 0.5-1.0 SE postoperatively, where 7.4-14.9% of eyes gain 1 line at 6 months follow up. Corneal haze/opacity grade 1 was observed in 8-51% at 1 week, and non of the monitored eyes showed haze grade 2 during the entire follow up. CNFL and CTBD were lower in KLex compared to Fs. LASIK and TransPRK and more prominent increase in CTBD at 6 moths postoperatively was observed in the TransPRK group.
Conclusions
All methods showed high safety and efficacy in correcting myopia where KLex and Fs. LASIK has better predictability and faster visual recovery. TransPRK and KLeX are less invasive procedures,requering less corneal tissue removal in comparison to Fs. LASIK. Although TransPRK can produce postoperative pain and discomfort, and has slower visual recovery in the first postoperative weeks, at 3 months postoperatively there was no difference in visual and refractive results between the methods. KLeX showed better and faster subbasal nerve plexus regeneration indicating it is less likely to induce subjective and objective symptoms associated with dry eye.