ESCRS - FP25.04 - Quantitative Assessment Of Post-Phacoemulsification Inflammation In Cataract Patients On Tamsulosin Therapy

Quantitative Assessment Of Post-Phacoemulsification Inflammation In Cataract Patients On Tamsulosin Therapy

Published 2025 - 43rd Congress of the ESCRS

Reference: FP25.04 | Type: Free paper | DOI: 10.82333/z66x-df38

Authors: David Beckers* 1 , Lena Beckers 1 , Florian Kretz 1 , Karen Glandorf 1 , Detlev Breyer 2

1Precise Vision Ophthalmologists,Rheine,Germany, 2Breyer, Kaymak, Klabe Ophthalmic Surgery,Düsseldorf,Germany

Purpose

To evaluate quantitatively the postoperative inflammation in patients at risk of intraoperative floppy iris syndrome(IFIS) during phacoemulsification surgery and to compare phacoparameters and inflammation parameters with uncomplicated phacoemulsification surgery.

Setting

Tertiary referral hospital

Methods

Between January 2023 and January 2024, patients under tamsulosin therapy prior to phacoemulsification surgery (Group 1) and uncomplicated cataract surgery with no additional features as a control group (Group 2) were prospectively included in this study. Phacoemulsification parameters, preoperative and postoperative best corrected visual acuity (BCVA-logMAR), intraocular pressure (IOP-mmHg), anterior chamber flare (ACF), central macular thickness (CMT), central choroidal thickness (CCT) and macular choroidal vascular index (mCVI) values were recorded.

Results

The study included 40 eyes in Group 1 and 42 eyes in Group 2.Total case time(Group 1: 20.61 min,Group 2: 16.35 min),total U/S time(Group 1: 1.10 min, Group 2: 0.88 min),total CDE(Group 1: 9.20,Group 2: 7.55) were significantly higher in Group 1(p<0.05 for all).Postoperative 1st day ACF was significantly higher in Group 1(21.62 ph/ms) compared to Group 2(17.53 ph/ms)(p=0.04).No difference was found between the two groups in terms of ACF at 1 week,1 month and 6 months postoperatively.There was no difference in CMT and CCT values in the postoperative period compared to the preoperative period in both groups.Also,preoperative and postoperative 1st week,1st month and 6th month mCVI were similar(p=0.95 p=0.25 p=0.43 p=0.79,respectively).

 

Conclusions

Patients receiving tamsulosin prior to phacoemulsification surgery exhibited higher phacoparameters compared to the control group, leading to an increase in ACF during the early postoperative period. However, tamsulosin use did not significantly impact posterior segment inflammation.