Corneal Endothelial Cell Changes After Ahmed Valve And Molteno Glaucoma Implants
Published 2025 - 43rd Congress of the ESCRS
Reference: FP22.09 | Type: Free paper | DOI: 10.82333/g34n-ac32
Authors: Gus Gazzard* 1 , Marc Toeteberg-Harms Toeteberg-Harms 2 , Iqbal K. Ahmed 3 , Eric Lam 4 , John Liu 5
1Glaucoma,NHIR Biomedical Research Centre, Moorfields Eye Hospital ,London,United Kingdom;Glaucoma,UCL Institute of Ophthalmology,London,United Kingdom, 2Department of Ophthalmology & Visual Sciences,University of Iowa,Iowa City,United States, 3Ophthalmology and Vision Sciences, University of Toronto, Mississauga,Toronto,Canada, 4Avania Market Access,Marlborough,United States, 5Elios,Irvine,United States
Purpose
To compare changes in corneal endothelial cell (CEC) indices 24 months after Ahmed valve (New World Medical, Inc., Rancho Cucamonga, CA) and single-plate Molteno implants (Molteno Ophthalmic Limited, Dunedin, New Zealand).
Setting
Imam Hossein Medical Center, Tehran, Iran.
Methods
This cohort included Ahmed valve (29 eyes) or single-plate Molteno (28 eyes) implants. Preoperative and postoperative central CEC indices were compared. Main outcome measure was endothelial cell count.
Results
Twenty-four months postoperatively, no difference in visual acuity improvement or decrease in antiglaucoma medications was observed between groups. The Molteno group showed better postoperative intraocular pressure control (P < .001). An 11.52% (Ahmed) and 12.37% (Molteno) reduction in CEC density (cells/mm2)) and 3.78 (Ahmed) and 2.48 (Molteno) increase in CEC area (mm2)) was observed, but no significant between-group difference in CEC density and area or corneal thickness.
Conclusions
Twenty-four months after Ahmed valve or Molteno implant, statistically significant quantitative (cell density) and minor qualitative (cell area) changes in central CEC were observed. Both groups appeared to have similar CEC damage.