Influence Of Posterior Vitreous Detachment On Retinal Detachment After Lens Surgery In Myopic Eyes - 5-Year Results Of The Escrs Myopred Study

Published 2025 - 43rd Congress of the ESCRS

Reference: FP12.03 | Type: Free paper | DOI: 10.82333/88tm-wg86

Authors: Kjell Gunnar Gundersen* ¹

¹Eye,iFocus Øyeklinikk ,Haugesund,Norway

Purpose

To assess the influence of the preoperative posterior vitreous detachment (PVD) status on the incidence of retinal detachment (RD) after lens surgery in myopic eyes over a period of 5 years.

Setting

Prospective multicenter study at 10 active European study centers: the European Society of Cataract and Refractive Surgeons (ESCRS) MYOpic Pseudophakic REtinal Detachment (MYOPRED) study

Methods

618 eyes of 618 patients with an axial length of ≥25.0 mm scheduled for lens surgery were recruited. Fellow eyes fulfilling the criteria of study eyes were additionally evaluated. Preoperatively and at each follow-up visit funduscopy and optical coherence tomography (OCT) were performed, at sites participating the substudy, also ultrasound if the hyaloid was not visible on OCT. Patients with preexisting complete PVD had one follow-up visit 2 months and telephone interviews (TI) 1, 2, 3 and 5 years postoperatively; patients without had follow-up visits at 2, 6 and 12 months and TIs at 2, 3 and 5 years. To identify relevant surgical procedures patients were invited to unscheduled visits or relevant surgical reports were sent for verification.

Results

Mean age was 64.8±9.9 years (range 23-92), 48.3% were female and 51.7% male (n=600). Median axial length was 26.1 mm (IQR 25.5-27.4, n=600) in the study eyes and 26.4 mm (IQR 25.6-27.7, n=368) in the eligible fellow eyes. During the 3-year follow-up, 14 RDs occurred (9 study eyes, 5 eligible fellow eyes). The estimated cumulative incidence rate for eyes with complete PVD at baseline was 0.2% at 1 year, 0.4% at 2 years and 0.4% at 3 years, for eyes with no or incomplete PVD 1.7%, 2.3% and 3.4%, respectively. Unadjusted the subdistribution hazard ratio was 6.14 (95% CI: 1.73-21.75, p=0.005), adjusted by age 4.36 (CI: 1.05-18.06, p=0.042). Close-out visits are currently being conducted. The 5-year results will be presented in Copenhagen.

Conclusions

Myopic eyes without a complete PVD before lens surgery had a significantly higher RD incidence during the first 3 postoperative years. Conclusions regarding the 5-year outcome will be presented at the congress.