Prevalence And Associated Factors Of Nd:Yag Posterior Capsulotomy After Premium Iol Implantation: A Systematic Review And Meta-Analysis
Published 2025 - 43rd Congress of the ESCRS
Reference: FP09.01 | Type: Free paper | DOI: 10.82333/8grt-gv78
Authors: Hasan Samed Akkaya 1 , Emine Kilic Toprak 2 , Aysegul Cort 3 , Ibrahim Toprak* 1
1Ophthalmology,Pamukkale University,Denizli,Türkiye, 2Physiology,Pamukkale University,Denizli,Türkiye, 3Biochemistry,Pamukkale University,Denizli,Türkiye
Purpose
To assess the prevalence and associated factors of Neodymium:yttrium aluminum garnet (Nd:YAG ) posterior capsulotomy after premium intraocular lens (IOL) implantation.
Setting
Single center.
Methods
This systematic review and meta-analysis followed PRISMA 2020 guidelines. We searched PubMed, Embase, and Cochrane Library databases up to June 12, 2024, for studies reporting Nd:YAG posterior capsulotomy prevalence after premium IOL implantation with follow-up at 6, 12, or 24 months postoperatively. This review has been registered in the International Prospective Register of Systematic Reviews (PROSPERO).
Results
A total of 129 studies with 14048 eyes met the inclusion criteria. The prevalence of Nd:YAG posterior capsulotomy at 6 months postoperatively was 0.5%, at 12 months it was 3.7%, and at 24 months it reached 18.1%. Subgroup analysis revealed that patients implanted with silicone IOLs had the highest prevalence of Nd:YAG posterior capsulotomy at both 6 and 12 months postoperatively. Meta-regression showed that Nd:YAG capsulotomy prevalence was positively related to follow-up durations (p < 0.0001). Additionally, the prevalence was higher in patients who implanted with plate-loop/four-haptic IOLs (p = 0.014) and accommodative IOLs (p = 0.001).
Conclusions
Nd:YAG posterior capsulotomy prevalence increased over time after premium IOL implantation. Silicone, plate-loop/four-haptic, and accommodative IOLs were associated with higher risks of Nd:YAG posterior capsulotomy. These findings can guide clinicians in selecting optimal premium IOL to minimize postoperative complications and improve long-term patient satisfaction.