Canaloplasty Effectiveness Correlated With Viscoelastic Volume Delivered In Schlemm’S Canal
Published 2025 - 43rd Congress of the ESCRS
Reference: FP08.03 | Type: Free paper | DOI: 10.82333/bmev-th41
Authors: Riccardo Vinciguerra* 1 , Robert Herber 2 , Francesco Versaci 3 , Juan Arbelaez 4 , Jorge Alio Del Barrio 5 , Farhad Hafezi 6 , Renato Ambrosio 7 , Paolo Vinciguerra 8 , Frederik Raiskup 2 , Emilio Torres-Netto 6
1Humanitas San pio X,Milan,Italy, 2Department of Ophthalmology, University Hospital Carl Gustav Carus,Dresden,Germany, 3Costruzione Strumenti Oftalmici,Firenze,Italy, 4Muscat Eye Laser Center,Muscat,Oman, 5Vissum Miranza,Alicante,Spain, 6ELZA institute,Zurich,Switzerland, 7Department of Ophthalmology, Federal University the State of Rio de Janeiro,Rio De Janeiro,Brazil, 8Humanitas University,Milano,Italy
Purpose
To investigate the effectiveness and correlation of pressurized ophthalmic viscoelastic device (OVD) volume delivered during ab-interno canaloplasty to reduce IOP in glaucomatous eyes.
Setting
Multicenter cloud-based database (iTGDR, part of the International Glaucoma Surgery Registry).
Methods
Eyes with glaucoma diagnosis and with ≥270° microcatheter circumnavigation of Schlemm’s canal were included. All patients underwent ab-interno canaloplasty via iTrack or iTrack Advance (Nova Eye Inc). Eyes were stratified based on OVD used (Healon; Healon GV; Healon Pro) and by amount of microboluses delivered (25-39; 40-59; 60-80). Complete success was defined as IOP reduction ≥20% or more with no increase in medication use or IOP ≤18 mmHg with no medications.
Results
225 eyes have been enrolled at baseline. Postop data was taken from the last observation (mean follow-up: 21.4±7.2 months). Mean OVD volume delivered was 117.1±26.5 µl or 46.8±10.6 microboluses (range: 53-175 µl or 21-70 microboluses). Complete success was 54%, 66% and 61% in the groups 25-39, 40-59 and 60-80 microboluses respectively. When stratified by OVD type, the group 40-59 microboluses returned the highest percentage of complete success in each OVD used. IOP spikes at day 1 were 7.7% for Healon, 8.3% for Healon GV and 8.8% for Healon Pro.
Conclusions
Findings suggest that 40-59 microboluses or 100-148 µl of OVD delivered in Schlemm’s canal result in the best outcomes for lowering IOP and medications.