Comparison Of Clinical Outcomes For Three Presbyopia-Correcting Iols: A Single-Center Prospective Study

To compare VA, defocus curve and patient-reported satisfaction with 2 types of Increased Range of Focus (Alcon Vivity, J&J PureSee) and a novel spiral full range of vision intraocular lens (Rayner RayOne Galaxy)  in cataract or lens-exchange surgeries.

Single site prospective study  - IRCCS Policlinico San Donato Hospital, Milan Italy

The study included 180 eyes for 90 patients. Preoperatively and postoperatively at 1 month visual outcomes were assessed. Preoperatively, a slit lamp examination, keratometry and biometry, as well as subjective refraction was performed. The follow-up visit after surgery included subjective refraction and visual acuity testing for far (4m), intermediate (66cm) and near distance (40cm) (ETDRS charts).  Dysphotopsia evaluation and Patient Satisfaction were also assessed with a questionnaire.

RayOne Galaxy exhibited superior uncorrected near visual acuity compared to Alcon Vivity and J&J PureSee. (UNVA: 0.06±0.2 logMAR (Galaxy) vs 0.30±0.10 logMAR (PureSee) vs 0.23±0.12 logMAR (Vivity) )

According to Halo/Glare and Subjective Patient Satisfaction Questionnaire score, all IOLs provided high patient satisfaction, showing minimal differencies. RayOne Galaxy ranked highest in spectacle independence at near. (89% (Galaxy) VS 40% (PureSee) 36%(Vivity)

Based on our experience, while all IOLs demonstrated substantial visual performance for distance and intermediate, better Uncorrected and Corrected near visual acuity were observed in the Galaxy Group. Galaxy was more likely to achieve spectacle independence at near visual acuity. Subjective visual disturbance and patient satisfaction yielded comparable results between groups.

This indicates a potential advantage of the novel spiral IOL, that provides high levels of spectacle independence while maintaining good quality of vision.