Spectacle Independence And Visual Outcomes After Bilateral Implantation Of A Edof Iol Compared To A Monofocal Iol: A Randomized Clinical Trial
Published 2025 - 43rd Congress of the ESCRS
Reference: FP05.06 | Type: Free paper | DOI: 10.82333/8byq-j188
Authors: Merce Guarro* 1 , Kamal Das 2
1Ophthalmology,OMIQ Research,Sabadell,Spain;Ophthalmology,Hospital General de Granollers,Granollers,Spain, 2Research,Alcon Research LLC,Fort Worth,United States
Purpose
To evaluate patients’ spectacle independence and visual outcomes after bilateral implantation of LuxSmart IOL (EDOF) compared to bilateral implantation of LuxGood IOL (Monofocal).
Setting
Ophthalmology Clinic, Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy
Methods
This randomized single blind clinical trial included 30 patients without ocular comorbidities other than cataract who underwent cataract surgery. Fifteen patients received bilateral LuxSmart IOL (EDOF) while the other 15 patients were implanted bilaterally with a LuxGood IOL (Monofocal). Three-months follow-up included: distance corrected and uncorrected visual acuity at 4m (DCVA and UDVA), 80cm (DCI80VA and UI80VA), 60 cm (DCI60VA and UI60VA) and 33cm (DCNVA and UNVA), binocular defocus curves, contrast sensitivity (CS), objective visual quality (Root mean square-RMS, point-spread-function -PSF- Strehl ratio) and the NEI RQL 42 questionnaire was administered.
Results
EDOF group demonstrated excellent visual acuity at intermediate distances compared to Monofocal group. The differences between the mean uncorrected monocular and binocular UI80VA and UI60VA were statically significant (p=0,008, p=0,006 and p=0,03, p=0,04, respectively). The differences between the mean corrected monocular and binocular CI80VA and CI60VA were statically significant (p=0,0005, p=0,0008 and p=0,001, p=0,001, respectively). The defocus curve for EDOF IOL was higher than that of Monofocal IOL, with statistically significant differences (p<0,05) observed at defocus levels from -1.00 D to -3.50 D. Subjectively, the patients were more satisfied of their far and intermediate vision and were more spectacle independent in EDOF group.
Conclusions
In this study both groups achieved very good visual acuities at far distance, with the EDOF group performing better in the intermediate distances. The EDOF group experienced the highest grade of satisfaction after three months and resulted to be more spectacle independent.