Difference In Visual Performance Of A Refractive Extended Depth Of Focus Intraocular Lens In An Emmetropic Or Monovision Modality.

The aim of this study was to compare the visual performance of a refractive intraocular lens (IOL) with extended depth of focus, namely the ZEN00V (TecnisPuresee, Johnson and Johnson), set for emmetropia (EMM) or mini-monovision (MON).

Vienna Institute for Research in Ocular Surgery(VIROS), Hanusch Hospital, Vienna, Austria

This study was designed as a randomized, patient- and examiner-masked, single-center study. In total 120 eyes of 60 patients will be included into this study. The first predicted minus IOL (Barret TK formula) was chosen for emmetropia, while the IOL for the non-dominant eye (NDE) in the MON group was chosen to be with a predicted offset of -0.75 D. Binocular uncorrected (UCDVA) and best corrected distance visual acuity (BCDVA) at 4 meters was tested preoperatively, at 1 week and at 3-4 months postoperatively. Quality of vision questionnaire (QOV), binocular contrast sensitivity, testing for stereopsis and Uncorrected intermediate visual acuity (UIVA) at 66cm and near visual acuity (UNVA) at 40cm, was evaluated at the last follow-up visit.

So far, 19 patients (73%female/26% male), with a mean age of 66 ±10 years (37;78), have been included. BCDVA at 1 week postoperatively was 0.04±0.00 (-0.4) and -0.03±0.01 (-0.04; -0.02) at the 4-months visit, for the EMM and MON group, respectively. At the first, one week follow-up, the EMM group showed an SE for the dominant eye (DE) of -0.15±0.39 D (-0.88;0.63) and the NDE -0.06±0.46 (-0.75; 0.63) with a BCDVA of 0.0±0.1 logMAR (-0.20; 0.00) and -0.03±0.07 logMAR (-0.16; 0.10), respectively, while the MON group showed a spherical equivalent (SE) for the DE of 0.02±0.39 D (-0.5; 0.63) and -0.54±0.46 D (-1.13; 0.13) for the NDE with a BCDVA of -0.04±0.05 (-0.1; 0) logMAR and -0.05±0.09 logMAR (-0.20; 0.00), respectively.

Preliminary data at the first follow-up visit in 19 patients showed good visual performance in both groups at the 1-week visit. More conclusive, comparative data from the 4-months visit will be presented at the congress.