ESCRS - FP02.06 - A Question Of Accuracy - Comparing Outcomes Of Wavefront-Optimized And Wavefront-Guided Excimer Ablation Treatment

A Question Of Accuracy - Comparing Outcomes Of Wavefront-Optimized And Wavefront-Guided Excimer Ablation Treatment

Published 2025 - 43rd Congress of the ESCRS

Reference: FP02.06 | Type: Free paper | DOI: 10.82333/vfxn-be63

Authors: George Beiko* 1 , Samantha Miyoko Orr 2

1Ophthalmology,McMaster University,St. Catharines,Canada;Ophthalmology,University of Toronto,TorontoT,Canada, 2family medicine,University of Western Ontario,London,Canada

Purpose

This study aims to compare the accuracy and clinical outcomes of wavefront-guided (WFG) versus wavefront-optimized (WFO) excimer laser ablation for refractive correction. The objective is to determine which technique offers superior efficacy and safety for patients undergoing laser vision correction.

Setting

A prospective observational study was conducted with patients requiring refractive correction.

Methods

Participants underwent wavefront-guided and wavefront-optimized excimer laser ablation. Preoperative and postoperative assessments included uncorrected distance visual acuity (UDVA), best-corrected distance visual acuity (CDVA), higher-order aberrations (HOAs), and patient satisfaction. Statistical analyses compared the outcomes between the two groups to evaluate differences in visual acuity, accuracy, refractive stability, and incidence of HOAs. Follow-up assessments were conducted at 1 month, and 3 months postoperatively.

Results

The study included 122 eyes (61 patients). Both groups achieved comparable postoperative SEQ and DEQ (0.08 D vs. 0.11 D and 0.09 D vs. 0.14 D). Refraction within ±0.50 D was achieved in 100% (WFO) and 96.72% (WFG). Postoperative astigmatism ≤0.50 D was 100% (WFO) and 98.36% (WFG). Mean UDVA was 1.48 (WFO) vs. 1.41 (WFG), and CDVA was 1.52 (WFO) vs. 1.47 (WFG). Efficacy Index: 1.06 (WFO) vs. 1.01 (WFG), Safety Index: 1.12 (WFO) vs. 1.09 (WFG), showing high precision and safety for both techniques. 

Conclusions

Both wavefront-optimized (WFO) and wavefront-guided (WFG) excimer laser ablation provided excellent refractive accuracy, visual outcomes, and safety in patients undergoing laser vision correction. There is no recommendation to prefer WFG over WFO in standard patients.