Comparison Of The Effects Of Three Different Corneal Refractive Surgery Procedures On Anterior Chamber Aqueous Flare And Choroidal Vascularity
Published 2024 - 42nd Congress of the ESCRS
Reference: PP27.10 | Type: Free paper | DOI: 10.82333/xn8v-ee95
Authors: Gizem YAYLA AKINCILAR* 1 , Sibel AHMET 1 , Husna TOPCU 1 , Burcu KEMER ATIK 1 , Nilay KANDEMIR BESEK 1 , Ahmet KIRGIZ 1
1Ophthalmology,University of Health Sciences Turkey Beyoglu Eye Training and Research Hospital,Istanbul,Türkiye
Purpose
To evaluate and compare anterior segment inflammation and choroidal vascular index after photorefractive keratectomy (PRK), femtosecond laser-assisted in situ keratomileusis (FS-LASIK), and small incision lenticule extraction (SMILE).
Setting
University of Health Sciences, Beyoglu Eye Training and Research Hospital, Beyoglu, Istanbul Turkey
Methods
This study included 123 eyes of 123 patients who underwent corneal refractive surgery between 2022 and 2023. The patients were divided into 3 groups as PRK, FS-LASIK, and SMILE. Preoperative manifest refractive values and corrected distance visual acuity (CDVA) were recorded. Aqueous laser flare meter (FC-700, Kowa Co. Ltd, Tokyo, Japan) was used to measure anterior chamber inflammation at preoperative and postoperative day 3, week 1, and month 1. Choroidal vascular index (CVI) was obtained preoperatively, at 1 week and 1 month postoperatively using enhanced depth imaging optical coherence tomography (Heidelberg Engineering, Germany) and ImageJ 1.51s software (National Institutes of Health, Bethesda, MD, USA).
Results
The study included 54 eyes in the PRK group, 45 eyes in the FS-LASIK group, and 24 eyes in the SMILE group. There were no significant differences between the groups in terms of preoperative and postoperative CDVA (p>0.05). However, there was a significant difference between the groups in terms of preoperative spherical and cylindrical values (each p<0.001). Aqueous flare measurements were similar in both preoperative and postoperative follow-ups and between the groups (each p>0.05). There was a significant difference in postoperative follow-up compared to preoperative CVI in all 3 groups (PRK p=0.013, FS-LASIK p=0.014, SMILE p=0.034). CVI values were similar for all follow-ups when the groups were compared (each p>0.05).
Conclusions
Corneal refractive surgery is a safe procedure that does not cause dysfunction of the blood-aqueous barrier or inflammation in the anterior chamber. However, it may cause fluctuations in choroidal vascularity.