ESCRS - PP25.10 - Long-Term Clarity After Implantations Of Hydrophobic Acrylic Intraocular Lenses With Hydroxyethyl Methacrylate: Randomized 3-Year Comparison

Long-Term Clarity After Implantations Of Hydrophobic Acrylic Intraocular Lenses With Hydroxyethyl Methacrylate: Randomized 3-Year Comparison

Published 2024 - 42nd Congress of the ESCRS

Reference: PP25.10 | Type: Poster | DOI: 10.82333/2d86-3t37

Authors: Akira Miyata* 1 , Kazunori Miyata 2 , Keiichiro Minami 2

1Miyata Eye Clinic,Hiroshima,Japan, 2Miyata Eye Hospital,Miyakonojo,Japan

Purpose

The randomized prospective study aimed to assess long-term clarity 3 years after implantation of hydrophobic acrylic intraocular lenses (IOLs) with hydroxyethyl methacrylate (HEMA).

Setting

Miyata Eye Clinic and Miyata Eye Hospital, Japan

Methods

For 116 eyes of 116 participants, one-piece Clareon IOLs with HEMA (SY60WF, Alcon, group C) or one-piece hydrophobic acrylic Vivinex IOLs (XY1, Hoya, group V) were randomly implanted during cataract surgery, and followed up for 3 years postoperatively. Best corrected visual acuity (BCVA) and contrast sensitivity were examined. Developments of posterior capsule opacification (PCO), microvacuoles (MVs) due to glistenings, and densitometry of IOL central surface (Pentacam) due to subsurface nano-glistening after mydriasis were also evaluated. PCO was quantitatively evaluated using EPCO 2000 software and MVs were counted within a 15 mm (length) x 4 mm (width) area in slit-lamp microscopy. Outcomes were compared between groups.

Results

There were 58 eyes in each group eligible for comparison. At 3 years postoperatively, the mean BCVAs of groups C and V were -0,06 (SD: 0.10) and -0,07 (SD: 0.09) logMAR (P=0.65), and there were no differences in BCVA and contrast sensitivity. PCO was observed in 40% and 47% of eyes, respectively, and three eyes each underwent Nd:YAG laser posterior capsulotomy. There was no difference in EPCO analysis results. MVs were found in three eyes each, and the numbers of MVs were four or less. The mean densitometry was 3.98% (SD: 0.69%) and 3.70% (SD: 0.61%); group C was higher (P=0.027) and increase significantly from ones at a visit of 1 weak to 1 month, while the increase was slight (0.29%).

Conclusions

Postoperative BCVA, and the developments of PCO, glistenings, and surface light scattering, were non-inferior or comparable between the two IOLs. The 3-year observation confirmed sustaining of long-term clarity of Clareon IOLs with HEMA.