ESCRS - PP24.06 - 10-Year Clinical Outcomes Of V4c Implantable Collamer Lens Implantation: Longitudinal Analysis Of Visual Acuity, Endothelial Cell Density, And Vault Dynamics

10-Year Clinical Outcomes Of V4c Implantable Collamer Lens Implantation: Longitudinal Analysis Of Visual Acuity, Endothelial Cell Density, And Vault Dynamics

Published 2024 - 42nd Congress of the ESCRS

Reference: PP24.06 | Type: Free paper | DOI: 10.82333/wr88-pq87

Authors: Byunghoon Chung* 1 , Soyoung Ryu 2 , David Kang 1 , Kangyoon Kim 1 , Tae-im Kim 2

1Eyereum Eye Clinic,Seoul,Korea, Republic Of, 2Ophthalmology,Yonsei University College of Medicine,Seoul,Korea, Republic Of

Purpose

This study aimed to evaluate the long-term clinical outcomes of V4c Implantable Collamer Lens (ICL) implantation for myopia correction over a 10-year period.

Setting

Retrospective observational study

Methods

The retrospective observational study, based on clinical practice, encompassed 103 myopic eyes from 54 patients. We assessed visual outcomes, including visual acuity and manifest refraction. Annual measurements of endothelial cell density (ECD), vault, anterior chamber depth, and intraocular pressure (IOP) were examined using mixed-effects models.

Results

At the 10-year mark, mean logMAR UDVA and CDVA were -0.037 ± 0.052 and -0.041 ± 0.046, respectively. Efficacy and safety indices stood at 1.11 ± 0.13 and 1.12 ± 0.12. CDVA loss of one line was noted in 2% of cases; however, 59% saw gains. MRSE was within ±0.5 D and ±1.0 D for 74% and 99% of patients, averaging at -0.19 ± 0.41 D. ECD and vault exhibited a slowing exponential decay over time, with rates of 0.012/year and 0.056/year, respectively. Lower ECD outliers had notably lower baseline ECD. No cataract, angle closure, glaucoma, or ICL removals reported.

Conclusions

Ten-year outcomes of V4c ICL implantation indicate effective and safe visual results. Both ECD and vault exhibited an exponential decay pattern over the decade. Patients with lower preoperative ECD particularly require careful monitoring post-implantation.