Adjunct Dried Amnion, In Athens Protocol(Combined Therapeutic Surface Excimer Normalization With Higher Fluence Cxl: Apcxl) For Keratoconus: A Comparison Study
Published 2024 - 42nd Congress of the ESCRS
Reference: PP23.05 | Type: Free paper | DOI: 10.82333/jwmq-v284
Authors: Alexandros John Kanellopoulos* 1 , Anastasios John Kanellopoulos 2 , Nikolaos Christopoulos 1 , Athanasios Zisimopoulos 1
1Ophthalmology,LaserVision Ambulatory Eye Surgery Unit,Athens,Greece, 2Ophthalmology,LaserVision Ambulatory Eye Surgery Unit,Athens,Greece;Ophthalmology,NYU Med School,New York,United States
Purpose
To investigate safety, efficacy and stability of dried amnion used in APCXL
Setting
The Laservision Clinical and Research Institute, Athens, Greece
Methods
This study included 50 eyes that have undergone APCXL which were randomly divided in two groups; in group-A an adjunct amnion disc was used, under the bandage contact lens, while in group-B contact lens alone. Besides the subjective pain score, visual acuity, corneal keratometry, astigmatism, epithelial distribution and minimum corneal thickness were evaluated at the first postoperative day, the day of complete re-epithelization for each eye, 1, 3 and 6 months postoperatively.
Results
Mean Values: Pain score group a 0.5 (1-4) while group B 1 (P<0.02), Epithelization; day 5 vs. day 7 respectively. At 6 months there was statistically less anterior stromal scarring group A. The tomographic and visual function data were comparable between the 2 groups.
Conclusions
Thin amnion used as an adjunct bandage in AP CXL may accelerate re-epithelization, improve first day pain profile and also improve epithelial remodeling within the first postoperative month.