Longterm Outcomes Of Accelerated Collagen Cross Linking 18Mw/Cm2 For 5 Minutes Protocol In Indian Pediatric Population
Published 2024 - 42nd Congress of the ESCRS
Reference: PP23.02 | Type: Free paper | DOI: 10.82333/7na7-fc20
Authors: Krishnaja Mandava* 1 , Himanshu Matalia 2 , Nandini C 2 , Rohit Shetty 1
1cornea and refractive surgery,Narayana Nethralaya,Bangalore,India, 2Cornea, cataract and Refractive surgery,Narayana Nethralaya,Bangalore,India
Purpose
To evaluate the visual and topographic outcomes following Accelerated Collagen Cross linking (ACXL) 18 mW/cm2 for 5 mins protocol in Indian Pediatric Keratoconus (KC) population.
Setting
A prospective study on progressive keratoconus patients under 18 years of age in a single centre of a tertiary care hospital in india from 2017-2021.
Methods
A prospective study on progressive keratoconus patients under 18 years of age in a single centre of a tertiary care hospital in india from 2017-2021.
382 eyes of 215 progressive keratoconus patients underwent epithelium off Accelerated collagen cross linking (18mW/cm2 for 5 mins ) protocol.
Uncorrected, and best corrected visual acuity, objective and manifest refraction were noted.
Patients with progressive keratoconus with clear cornea with reliable topography and minimum of 1 year follow up post surgery were included, while patients with subepithelial/ corneal scarring excluded from the study.
Cases were followed on 1 month, 3 months ,6 months, 1 year, 3 years, 5 years period post operatively.
Results
Statistically significant improvement of mean unaided, aided visual acuity, keratometry and mean corneal astigmatism (P< 0.0001) was noted.
Mean Maximun keratomtery(Kmax) reading reduced from 55.67+/- 6.2 (47.2-72.3)D pre-operatively to 54.13+/- 6.1(46-69.1)D at 1 year, 53.90+/-5.90D at 3 years and 53.50+/- 5.85D at 5 years.
Corneal densitometry values 3 months following surgery had significantly increased compared to baseline measurements.
There was significant increase in mean densitometry (P< 0.05).
The mean densitomtery decreased at 1 year, 3 years and 5 years.
Conclusions
Accelerated Collagen cross linking(ACXL) 18mW/cm2 for 5 mins protocol can halt the progression of Keratoconus in Indian pediatric population.