Fitting-Shape-Based Strategy For Topography-Guided Lasik: A Prospective Study

To assess and compare the visual acuity and refractive outcomes of topography-guided LASIK based on the fitting-shape-based refractive compensated and Phorcides software strategies.

Hangzhou MSK Eye Hospital

Consecutive patients who underwent topography-guided LASIK were included in this study. Through double-masked simple randomization, patients were assigned to the exposure group (the fitting-shape-based refractive compensated strategy using the ZZ AR calculator was used) or the control group (the topography analysis algorithm in Phorcides software was used). Only one eye per patient with binocular correction was randomly enrolled. The preoperative and postoperative visual acuities and refraction were analyzed at the 6-month follow-up.

The exposure and control groups comprised 156 and 147 eyes, respectively. At the 6-month postoperative follow-up, the absolute residual cylindrical refraction was 0.35 (1.01) D and 0.47 (1.63) D for the ZZ AR and Phorcides groups, respectively (P < 0.001). The percentages of patients with residual cylindrical power within 0.25 D were 29.49% and 13.61% for the ZZ AR and Phorcides groups, respectively (P = 0.001). Based on the percentages of patients with residual cylindrical powers within 0.50 and 1.00 D, the ZZ AR group showed better outcomes (P = 0.02 and P = 0.01). Besides, the percentage of patients with visual acuity above 20/16 was significantly higher for the ZZ AR group than for the Phorcides group (P = 0.03).

The fitting-shape-based refractive compensated strategy for topography-guided LASIK procedures can better optimize the visual acuity and astigmatic refraction than the Phorcides software strategy.