First Experience With Topography Guided Ablation Treatment Based On Oct Readings

To report on first experience with a personalized corneal driven excimer laser procedure called OCTAVIUS CT anterior. These are the first data on topography guided ablation treatment based on optical coherence tomography (OCT) readings performed with TECHNOLAS TENEO 317 Model 2 Excimer Laser Platform.

Clinique Ophtalmologique de Laser Excimer, Sousse, Tunisia 

This data collection includes a total of 81 eyes from 52 patients (29 bilateral, 23 monolateral) who have been treated with a new personalized corneal driven excimer laser procedure based on OCT readings. OCTAVIUS offers two treatment options with ablation being based on either anterior corneal topography (CT anterior) or total corneal (CT total) readings. Only CT anterior was used in this setting and data were available preoperatively and up to 1 month (1M) postoperatively. The examinations included manifest refraction as well as monocular visual acuity data on uncorrected distance visual acuity (UDVA) and best-corrected distance visual acuity (BCDVA).

The manifest spherical equivalent (SE) was reduced from -3.57±1.42 D (-7.75 to -0.95 D) preoperatively to 0.10±0.21 D (-0.25 to 0.75 D) 1M postoperatively. The manifest cylinder was reduced from -0.80±0.60 D (-3.00 to 0.00 D) to -0.06±0.16 D (-0.50 to 0.00 D), respectively. 98.8% of eyes were within ±0.5 D of their intended postoperative SE with 60% being within ±0.13 D. At their last postoperative visit 100% of eyes presented with UDVA of 0.0 logMAR and 32% reached -0.10 logMAR. For 70% of eyes there was an increase of one line compared to preoperative for BCDVA. In terms of binocular UDVA, 86% of the bilateral patients reached -0.10 logMAR and 21% -0.20 logMAR. For 45% of these patients there is a gain of 2 lines for BCDVA.

The first experience of performing a personalized anterior topography (CT anterior) driven excimer laser procedure using TENEO 317 Model 2 Excimer Laser Platform shows very promising outcomes. In terms of refraction the results were stable for the follow-up time of up to 1 month and visual acuity shows good outcomes which likely indicates great patient satisfaction. In the near future an Excimer treatment based on total topography readings (CT total) will be available too, enabling a versatile treatment.