Comparison Of Anterior And Posterior Segment Findings In Patients With A History Of Renal Transplantation Undergoing Cataract Surgery
Published 2024 - 42nd Congress of the ESCRS
Reference: PP05.15 | Type: Free paper | DOI: 10.82333/f843-cp11
Authors: Sena Karabay Kılıçarslan* 1 , Gülşah Gökgöz 1 , Ümit Ekşioğlu 1 , Meriç Yavuz Çolak 2 , Mehmet Haberal 3
1Ophthalmology,Başkent University Ankara Hospital,Ankara,Türkiye, 2Biostatistics,Başkent University,Ankara,Türkiye, 3General Surgery,Başkent University Ankara Hospital,Ankara,Türkiye
Purpose
With this study, we aim to investigate the anterior and posterior segment findings of end-stage renal disease patients who underwent cataract surgery after renal transplantation.
Setting
The ocular biometric measurements which were evaluated by ZEISS IOLMaster 700 (Carl Zeiss Meditec AG, Jena, Germany) were axial length (AL), white to white (WTW), anterior chamber depth (ACD), corneal keratometry (K1 and K2), degree of astigmatism, lens thickness (LT). Retinal thickness was measured and compared with healthy control subjects by optic coherence tomography (Heidelberg Spectralis OCT-Heidelberg Engineering, Heidelberg, Germany).
Methods
The study was designed cross-sectionally. Patients who underwent cataract surgery after renal transplantation in our hospital between December 2017-March 2023 were included.
Results
48 eyes of patients who underwent cataract surgery after renal transplantation and 48 eyes of control group were enrolled in the study.K1,K2 and LT parameters from biometric parameters were found to be statistically significantly higher in the transplantation group(p<0.001;p<0.001;p=0.002).AL and WTW were found to be significantly higher in the control group (p<0.001;p=0.021).There was a statistically significant difference in retinal thickness in preoperative all parafoveal quadrants(p=0.002;p=0.011;p<0.001;p=0.002)and inferior,temporal perifoveal quadrant measurements(p=0.012; p=0.059) and the postoperative foveal thickness average and all parafoveal quadrants(p<0.001),superior,nasal perifoveal quadrant measurements(p=0.045;p=0.004).
Conclusions
Our findings indicate altered anterior and posterior segment parameters in renal transplant patients compared to healthy individuals, potentially reflecting the impact of renal transplantation on ocular microcirculation and metabolism. These findings may inform strategies for selecting intraocular lens power during cataract surgery in this patient population. Further research with larger sample sizes is needed to explore the long-term implications of these changes and investigate potential associations with specific immunosuppressive medications.