A Novel Method To Optimize Personal Constants

To show a new online tool, ioloptimization.com, that allows ophthalmologists, without the need of technical knowledge, personalize their own IOL constants for new and classic formulas.

Centro Buonsanti, Buenos Aires, Argentina.

A dataset of 1,079 eyes was used to optimize. Formulas included were Barret UII, Cooke K6, Haigis, RBF 3.0, Hoffer Q, Hoffer QST, Holladay 1, Holladay 2, SRK/T and T2. The same dataset was also divided into 3 sub groups of eyes (short, medium and long eyes). The three variable optimization process was applied to each dataset and subset, and the obtained optimized constant was then used to obtain the mean prediction error of each dataset. We then compared those results witth those we obtained by zeroing out the ME in the classical method.

The three variable optimization showed similar results to classical optimization with less data needed to optimize and no clinically significant difference in a study done in 1079 eyes.

This method could then be applied by surgeons to optimize their constants by reducing the mean prediction error to zero without prior technical knowledge and it is available online for free. This may encourage ophthalmologists to optimize their constants and possibly achieve better refractive outcomes.