Comparison Of Contrast Sensitivity Between One And Two Repeated Measurements After Lenticule Removal Procedure

Published 2024 - 42nd Congress of the ESCRS

Reference: PP03.12 | Type: Free paper | DOI: 10.82333/ht0c-rp74

Authors: Raghav Malik* ¹ , Mahipal Sachdev ¹ , Rohit Shetty ² , Wee Jin Heng ³ , Brian Schwam ⁴ , Pooja Khamar ² , Ritika Sachdev ¹ , Michal Laron ⁵ , Andrew Voorhees ⁵ , Hong Fu ⁵ , Ying Wang ⁵ , Alejandra Gonzalez Calle ⁵ , Luis Vargas ⁵

¹Centre For Sight,Delhi,India, ²Narayan Nethralaya,Bengaluru,India, ³TTSH,Singapore,Singapore, ⁴JJSV,Florida,United States, ⁵JJSV,Milpitas,United States

Purpose

To evaluate the difference in contrast sensitivity (CS) between one measurement (group 1) versus the mean of two measurements (group 2) after lenticule removal procedure with the new femtosecond laser system: ELITA.

Setting

A prospective, multicenter, open-label, bilateral lenticule removal clinical study for myopic correction was performed

in 4 clinical sites.

Methods

One hundred and twenty subjects were treated with mean age of 26.6±5.9 SD. For each subject, a lenticule was created in both eyes using ELITA and was then removed for vision correction. Mean pre-op MRSE was -4.20D and ranged from -1.25D to -9.63D. Contrast sensitivity data was measured at pre-op, and then starting at the 3-month post-op visit. CS was measured and repeated twice in mesopic conditions with and without glare at 1.5, 3.0, 6.0, and 12.0 cpd; and in photopic conditions with no glare at 3.0, 6.0, 12.0. and 18.0 cpd. MRSE and monocular UCVA and BSCVA were assessed at those time points

Results

No significant CS difference was found between groups except at 6 M postop, a difference of 0.04 log units (mesopic, no glare, 3 cpd), and 0.05 log units (mesopic, glare, 12 cpd) was observed, below the clinically significant threshold of 0.3 log units. Preoperatively, the mean CS was 1.36 log units (photopic, no glare, 18 cpd) for both. Post op, CS remained consistent between groups: 1.36/1.35 (3M), 1.45/1.45(6M), 1.47/1.50 (9M), and 1.52/1.52 (12M). MRSE was -0.27D and -0.31D at 3 and 6M postop. Monocular UCVA/BSCVA was 20/20 or better for 93%/100% of eyes (3M), and 94%/99% of eyes (6M).

Conclusions

No significant difference in CS was found between group 1 and 2 after lenticule procedure. CS increased post op for the photopic condition at 18 compared to pre-op but it was not statistically significant. The good visual outcomes demonstrate that the ELITA system is safe and effective.