Peripheral Ulcerative Keratitis And Episcleritis As The Initial Signs Of Pancreatic Neoplasia
Published 2024 - 42nd Congress of the ESCRS
Reference: PO955 | Type: Free paper | DOI: 10.82333/1x18-mn43
Authors: Turki ABDULLAH Alghamdi* 1 , IBRAHIM ASIRI 2 , RANA ALOJAIR 1
1OPHTHALMOLOGY,ARMED FORCES HOSPITAL SOUTHERN REGION,KHAMIS MUSHAIT,Saudi Arabia, 2ANTERIOR SEGMENT FELLOW,KKESH,RIYADH,Saudi Arabia
Purpose
To report a rare ophthalmic manifestation of periampullary pancreatic tumor.
Setting
case report of periphral ulcerative keratitis (PUK)
Methods
We reported a rare case of 70 years old female patient with PUK as an ocular manifestation in the presence of underlying systemic solid organ malignancy. Ocular redness, pain, and photophopia are the major symptoms. Examination of right eye showed conjunctival injection, peripheral corneal infiltration which was treated by topical antibiotic, doxycycline and topical prepared medroxyprogesterone. Our provisional diagnosis was periphral ulcerative keratitis after ruling out infectious and autoimmune causes. During follow-up time, she presented with jaundice and recurrence of corneal symptoms. Laboratory results showed abnormal liver enzymes and amylase level. Histology of periampullary pancreatic tissue showed mucosal adenocarcinoma.
Results
The early diagnosis and appropriate management of PUK in patients with malignancies are vital to preserving sight and saving a life. This case highlights that, besides other infectious or autoimmune causes, PUK may be associated with life-threatening systemic solid pancreatic neoplasm.
Conclusions
PUK can be presenting manifestation of solid neoplasm that should be considered among differential diagnosis especially in elderly patient.