Case Report Of 360° Limbal Transplantation From Deceased Donor Assisted By Femtosecond Laser.

Present a case report of 360° limbal transplantation from a deceased donor assisted by femtosecond laser and evaluate its efficacy in treating total limbal insufficiency.

The case report describes the treatment of a patient with primary acquired melanosis with atypia, who developed superior limbal insufficiency progressively extending to all four quadrants, leading to peripheral conjunctivalization and associated epithelial alteration. The surgery took place in a clinical setting, likely in an ophthalmology department or specialized eye clinic.

The femtosecond laser was utilized to create lamellar annular cuts in both the donor and recipient tissues. Dissection was then manually extended towards the periphery using a crescent knife. The donor limbal graft was placed on the recipient cornea and sutured with 6 radial points to join the corneal tissue of the donor and recipient. Additionally, fixation of the donor conjunctiva to the scleral bed was performed using tissue adhesive. Amniotic membrane transplantation was also conducted. Post-surgery evaluations were performed to assess the ocular surface stability, visual acuity improvement, and pain relief.

Subsequent post-surgery evaluations revealed a stable ocular surface, improved visual acuity, and the absence of pain reported by the patient. The use of femtosecond laser-assisted transplantation resulted in successful treatment outcomes for total limbal insufficiency.

The case report demonstrates the efficacy of 360° limbal transplantation from a deceased donor assisted by femtosecond laser in treating total limbal insufficiency. The findings suggest that femtosecond laser technology can be utilized to produce uniform-thickness ring-shaped keratolimbal grafts, offering a promising approach for the management of eyes with extensive limbal insufficiency.