Effect Of Low-Level Led Therapy (Lllt) On Ocular Surface And Iop In Glaucoma Patients Under Treatment With Topical Prostaglandin Analogues.

Published 2024 - 42nd Congress of the ESCRS

Reference: PO926 | Type: Free paper | DOI: 10.82333/wmrw-tb54

Authors: Miguel Angel Teus* ¹ , Cristina Muñiz ² , Esther Arranz-Márquez ³

¹Universidad de Alcalá,Madrid,Spain;Novovisión Clinic,Madrid,Spain, ²Novovision Clinic,Madrid,Spain, ³Novovisión Clinic,Madrid,Spain;Hospital Rey Juan Carlos,Móstoles,Spain

Purpose

To report the results of a prospective study on ocular comfort (OSDI), and objective tear film parameters, NIBUT and eye redness (Keratograph) in primary open angle glaucoma (POAG) patients under chronic treatment with topical prostaglandin analogues.

Setting

Private clinical practice located in Madrid, Spain.

Methods

Prospective, single masked, interventional study. 35 POAG eyes were included. IOP measurement (Goldmann), OSDI test and Keratograph analysis of the tear film and eye redness were performed by a masked examiner before and 1 and 3 months, after two sessions of LLLT using the Meibomask® device.

Results

Mean age was 68.17±12.00 years, mean basal IOP was 14.29±2.78 mmHg. The OSDI improved significantly from 18.50±17.21 (baseline) to 10.11±10.52 and 12.44±14.57 at 1 and 3 months after treatment, respectively (p<0.05). On the other hand, the IOP significantly decreased from 14.29±2.78 mmHg at baseline to 12.96±2.53 mmHg and 13.32±2.50 mmHg at 1 and 3 months after LLLT, respectively (p<0.01).

No statistically significant difference in eye redness and NIKBUT (Keratograph®) was found at any time point as compared to baseline values.

Conclusions

LLLT using the Meibomask® device improves the ocular surface discomfort in POAG patients under topical prostaglandin therapy and induces a significant IOP decrease in these eyes that lasts at least for 3 months after LLLT treatment.