Improvement Of Dryness At The End Of The Day After One Week Of Using Systane Complete Preservative Free: Preliminary Results From A Multi-Centre Study
Published 2024 - 42nd Congress of the ESCRS
Reference: PO862 | Type: Poster | DOI: 10.82333/w3s8-ry06
Authors: Celia Rubio* 1 , Beatriz García-García 2 , Raquel García-Vico 3 , Carmelo Baños 4 , Carmen Gordón 5 , Irene Sánchez 6
1inGO Research Group,General Optica,Madrid,Spain, 2inGO Research Group,General Optica,Ponferrada,Spain, 3inGO Research Group,General Optica,Córdoba,Spain, 4Optometría y Visión,Universidad Complutense de Madrid,Burgos,Spain;inGO Research Group,General Optica,Burgos,Spain, 5Servicio de Oftalmología,Hospital Universitario de Burgos,Burgos,Spain, 6Departamento de Física Teórica, Atómica y Óptica,Universidad de Valladolid,Valladolid,Spain;Optometry Research Group,IOBA Eye Institute,Valladolid,Spain
Purpose
Ocular dryness is a prevalent issue that affects many people of all ages and is a problem that affects daily activity. The purpose of this study is to analyze the effect of Systane Complete Preservative Free (MDPF) on dryness symptomatology in daily tasks and to quantify it with DEQ-5 and OSDI questionnaire.
Setting
This is a prospective, multicenter, interventional, unmasked study performed in ten General Optica centres in collaboration with Valladolid University.
Methods
The study include patients (legal age) who attend in their annual check-up General Optica centers in Spain and present ocular dryness symptomatology in any daily task, reported in any DEQ-5 questionnaire item ≥2 and a OSDI score between 13 and 32 points. Patients had no ocular pathology and no ocular surgeries in the last year, with an EFRON score below 3 and no corneal staining (with sodium fluorescein) greater than 1 according to the Oxford scale, were included in the study. A compressive optometric examination, OSDI, and DEQ-5 Questionnaires were performed. Systane Complete MDPF was prescribed for 1 month to be used 4 times per day, one drop in each eye with a minimum interval of 3 hours and the last one 2 hours before bedtime.
Results
Preliminary results are presented from a cohort of 24 patients (average age of 45.58 years, range 20 to 63 years) comparing the initial visit with the first follow-up visit after one week of Systane Complete MDPF use. In this group, there were 12 myopes, 7 emmetropes and 5 hypermetropes. The DEQ-5 score has improved after one week of using Systane Complete MDPF from 11.29±3.38 points (range 4 to 16 points) to 5.25±3.61 points (range 0 to 13 points) and this improvement is statistically significant (p<0.01). Besides, the OSDI score also shows a statistically significant (p<0.01) decrease from 23.16±6.44 (range 14.58 to 32.00 points) to 10.82±7.91 points (range 0 to 27.08).
Conclusions
Systane Complete MDPF seems to be an effective treatment to reduce ocular dryness symptomatology in non-pathological patients. It enhances the sensation of ocular comfort, as measured by the OSDI scale, and alleviates end of day dryness, according to the DEQ-5 questionnaire, thereby improving the quality of life for users. Longer follow-up results are needed to see if this efficacy lasts over time.