ESCRS - PO847 - Determination Of Presence And Types Of Sleep Disorders In Dry Eye Disease Patients

Determination Of Presence And Types Of Sleep Disorders In Dry Eye Disease Patients

Published 2024 - 42nd Congress of the ESCRS

Reference: PO847 | Type: Poster | DOI: 10.82333/6a6v-yj51

Authors: Ana Nolla* 1 , Cecilia Salinas 1 , Karol Enrique Uscamaita 2 , Laura González 1 , Laura Zahiño 1 , Claudia Garrido 1 , Sandra Suescun 1 , Julia Ferrer 2

1Instituto de Microcirugía Ocular (IMO Barcelona) Grupo Miranza, Barcelona, Spain,Barcelona,Spain, 2Adsalutem Sleep Institute, Barcelona, Spain,Barcelona,Spain

Purpose

In the course of a prospective observational study, to describe, through objective measurements, the presence and type of sleep disorders in patients diagnosed with Dry Eye Disease (DED). 

Setting

Instituto de Microcirugía Ocular Grupo Miranza, Barcelona (Spain) and Adsalutem Instituto del Sueño, Barcelona (Spain)

Methods

Patients diagnosed with DED underwent standard ocular tests, including the Ocular Surface Disease Index (OSDI) questionnaire, Tear Break-up Time (BUT), tear osmolarity, corneal fluorescent staining (Oxford scale), Schirmer test, and McMonnies scale for hyperemia assessment. Sleep-related assessments included structured interviews by a sleep disorder specialist, self-completion questionnaires (Pittsburgh Sleep Quality Index, Epworth Sleepiness Scale, Insomnia Severity Index, and STOP-Bang), a 2-week sleep diary, actigraphy, and polysomnography.

Results

Thirty subjects were included (73% women, average age: 50) and sleep quality evaluation revealed prevalent sleep disorders, including chronic insomnia (70%), altered apnea-hypopnea index (38.46%), restless legs syndrome (13%) and insufficient sleep (7%). Only 17% had no significant sleep alterations. Statistical analysis revealed significant correlations between dry eye severity and adverse sleep quality, shorter time of Slow Wave Sleep (N3), higher rate of AHI scores, reduced oxygen saturation levels, and diminished sleep efficiency (p<0.05).

Conclusions

Sleep disorders are common among patients with DED. The main sleep disorder shown by DED patients in our study was chronic insomnia, while some rare sleep disorders like nocturnal lagophthalmos can be present.