The Effectiveness Of Intense Regulated Pulse Light (Irpl-E>Eye) In The Treatment Of Evaporative Dry Eye Disease Among Malaysian Asians: A Pre And Post Visit Comparative Study
Published 2024 - 42nd Congress of the ESCRS
Reference: PO841 | Type: Poster | DOI: 10.82333/hr7q-7b80
Authors: Aloysius Joseph Low* 1 , Azarina Abdullah 2 , Nur Sabrina Subri 3
1Medical Director ,VISTA Eye Specialist,Selangor,Malaysia, 2Clinical Development Manager,VISTA Eye Specialist,Selangor,Malaysia, 3Senior Lecturer, Faculty of Health Sciences,Universiti Teknologi MARA,Puncak Alam,Malaysia
Purpose
Evaporative dry eye disease primarily caused by meibomian glands dysfunction (MGD) may vary within different ethnicities at a high prevalence. This has been reported among Asians. Intense Regulated Pulsed Light (IRPL) therapy by ESW Vision (known as E>Eye) is designed to stimulate the parasympathetic nerves connected to the meibomian glands, promoting neurotransmitter release, gland secretion, and contraction to help treating dry eye disease caused by MGD.
This study aims to investigate the effectiveness of IRPL in treating evaporative dry eye due to MGD among Malaysian Asian patients using Tear Check analyzer in three consecutive treatments.
Setting
All patients were examined pre and post treatment at VISTA Eye Specialist, Malaysia by a single Ophthalmologist. Equipment used in the data collection were Tear Check Analyzer by ESW Vision and slit lamp biomicroscopy.
Methods
71 male and 107 female patients, aged between 28-83 with complaints of dry eye symptoms accompanied by clinical signs of MGD were included in the study. All patients were treated with IRPL in three consecutive treatments by administering five overlapping flashes of light on the lower lid and temporal part of each eye on day 1 (D1), 15 (D15) and 45 (D45). Improvement in lower meibomian gland loss, Tear Film Stability Evaluation (TFSE) and non-invasive break up time (NIBUT) were assessed using Tear Check analyzer pre and 6 weeks post treatment.
Results
Repeated-measure ANOVA showed that the percentage of lower meibomian gland loss and TFSE score were significantly improved post-treatment indicating recovery of the meibomian gland and improved tear stability. McNemar Change Test also showed that the percentage of patients having NIBUT of lower than 6 seconds has significantly reduced post-treatment.
Conclusions
IRPL-E>Eye is effective in treating evaporative dry eye disease caused by MGD in Malaysian Asian patients with three consecutive treatments.