Small Customized Incision Allogeneic Lenticule Implantation Combined With Corneal Cross Linking For Keratoconus With Thin Cornea
Published 2024 - 42nd Congress of the ESCRS
Reference: PO792 | Type: Free paper | DOI: 10.82333/ftt2-7e86
Authors: Kangjun Li* 1 , Zhanyu Su 2 , Siya Li 1 , Shanshan Wang 1
1Northwest University,AIER EYE hospital,XI'AN,China, 2Central South University, AIER School of Ophthalmology,Changsha,China
Purpose
To describe a technique for the treatment of advanced keratoconus with thin cornea using small customized incision allogeneic lenticule implantation (SCI-Li) combined with corneal cross-linking (CXL).
Setting
Clinical observation study
Methods
A total of 19 eyes of 19 advanced keratoconus patients with corneal thickness less than 400μm were enrolled for the study. Preoperative and postoperative parameters measured include visual acuity, manifest refraction spherical equivalent, slit-lamp exam, anterior segment optical coherence tomography (AS-OCT), Pentacam AXL corneal topography and Corvis ST measurement.
Results
During the 12-month follow-up, no adverse event was observed in any of the eyes and the lenticule was well positioned in all eyes in the intrastromal pocket identified by the slit-lamp and the AS-OCT imaging. Statistically significant increase in corneal thickness (P < 0.001) was observed with significant decrease in corneal curvatures at the apex (P < 0.001). The corneal stiffness was shown to be statistically significantly increased by a rise in SP-A1 and SSI and a drop in DA ration (all P < 0.001).
Conclusions
SCI-Li combined with CXL is a safe and effective method in restoring corneal structure and biomechanics in advanced keratoconus eyes with thin corneas.