ESCRS - PO779 - Clinical Outcomes After Sutureless Keratoplasty In Progressive Corneal Diseases In A 5 Years Follow-Up Study

Clinical Outcomes After Sutureless Keratoplasty In Progressive Corneal Diseases In A 5 Years Follow-Up Study

Published 2024 - 42nd Congress of the ESCRS

Reference: PO779 | Type: Free paper | DOI: 10.82333/g691-bp64

Authors: Faruk Semiz* 1 , Njomza Hima Musa 1 , Ceren Ece Semiz 1 , Fetih Furkan Arslan 2 , Zekeriya Alp Demirsoy 1

1ophthalmology,Eye Hospital,Pristina,Kosovo, 2ophthalmology,Istanbul university-Cerrahpasa,Istanbul,Türkiye

Purpose

 Our study aims to investigate the feasibility and effect of intrastromal fresh lenticule keratoplasty (Sutureless keratoplasty) as an allogeneic graft. To implant in keratoconus patients taken from myopic patients using VisuMax Femtosecond laser-Smile module surgery. Also, the primary aim is to increase the central corneal thickness and secondarily to improve visual acuity by changing the corneal shape (Q value) from conical to ellipsoid form.

Setting

Eye Hospital,Kosovo

Methods

All the patients were clinically diagnosed with progressive keratoconus. Forty eyes (twenty patients) underwent SMILE surgery (donor group), and forty eyes underwent sutureless keratoplasty with a smile module (recipient group). Visual acuity, corneal topography, and anterior segment optical coherence tomography were analyzed.

Results

Visual acuity, preoperative CDVA improvement from 1 ± 0 logMAR to 0.55 ± 0.09 logMAR ( P < 0.001). The preoperative K1 values decreased from 56.25 ± 0.94 D to 51.71 ± 0.68 D (P < .001), whereas K2 values decreased from 63.53 ± 1.40 D to 54.88 ± 0.96 D (P < .001).

The preoperative CCT increased from 338.35 ± 11.24 µm to 484.95 ± 5.00 µm (P < .001).

Conclusions

In this study both corneal central thickness and visual acuity improved by changing in corneal shape (Q Value) from conical form to ellipsoid.  The efficacy and safety of FML intrastromal sutureless keratoplasty as a new surgical technique in patients indicated for penetrating keratoplasty were demonstrated based on this study's long-term follow-up results.

 

ClinicalTrials.gov Identifier: NCT04591587