A Case Report Of A Descemet Stripping Only And Rho Kinase Inhibitors In A Hospital In Seville, Spain

Our main objective is to describe a case of cataract surgery with descemetorhexis and rho-kinase inhibitors in our hospital.

Report of a case from the Virgen de Valme University Hospital in Seville (Spain),

Description of the patient's evolution from the diagnosis, through the surgical technique and the subsequent result.

We present the case of a 54-year-old woman who presented with decreased visual acuity. She was diagnosed with mild amblyopia in OD. VA on decimal scale was OD 0.3 OS 0.5. We observed in both eyes corneal guttate and posterior subcapsular cataract. We evaluated the periphery of the cornea where we found that the endothelial pattern was quite preserved in contrast to the center. We indicated the technique of descemetorhexis without grafting together with cataract and associated treatment with ripasudil 4 times a day for two weeks. We showed in biomicroscopy how the edema evolved, with total resolution after 4 weeks. Currently she has a VA in that eye of 0.8, the central endothelial pattern has recovered and she is very satisfied.

DSO is a useful surgical technique in patients with Fuchs distrophy. DSO avoids some of the problems associated with endothelial transplantation, which is currently the gold standard like a primary graft failure, a graft dislocation and a waiting with the availability of donor tissue. The use of rho-kinase-associated inhibitors is under study in Fuchs' dystrophy since it has been shown that their use in vitro and topical in vivo is able to increase migration, proliferation and adhesion of endothelial cells. In this case we show how they worked correctly in a case in our hospital, so we believe that they should be considered as a good option in selected cases.