ESCRS - PO726 - Prospective Assessment Of Demographic And Clinical Characteristics In Herpes Zoster Ophthalmicus Patients At Tertiary Eye Hospital

Prospective Assessment Of Demographic And Clinical Characteristics In Herpes Zoster Ophthalmicus Patients At Tertiary Eye Hospital

Published 2024 - 42nd Congress of the ESCRS

Reference: PO726 | Type: Poster | DOI: 10.82333/7x2b-q974

Authors: Nikhil Agrawal* 1 , Kavita Bhatnagar 2 , Kavita Bhatnagar 3 , Kirti Jaisingh 3 , Sambit Patra 2 , Manjari Tandon 2 , Sambit Patra 4 , Seema Meena 2 , Kirti Jaisingh 2

1Ophthalmology,AIIMS Jodhpur,Jodhpur,India;Ophthamology,AIIMS Jodhpur,Jodhpur,India, 2Ophthalmology,AIIMS Jodhpur,Jodhpur,India, 3Ophthamology,AIIMS Jodhpur,Jodhpur,India, 4Dermatology,AIIMS Jodhpur,Jodhpur,India

Purpose

To undertake a prospective analysis of the clinical manifestations and demographic distribution of Herpes Zoster Ophthalmicus (HZO) within a cohort at the All India Institute of Medical Sciences (AIIMS) Jodhpur, delineating theepidemiological trends, clinical presentations, and outcome measures over a one-year follow-up period.

Setting

The study was conducted collaboratively between the Department of Ophthalmology and the Department of Dermatology at AIIMS Jodhpur.

Methods

A cohort of 42 individuals presenting with HZO underwent a comprehensive evaluation to document theirdemographic data, clinical features, and associated risk factors. These patients were monitored longitudinally over a 12-month period to record the incidence of recurrence and to identify any sequelae resulting from the condition.

Results

Results: In a study at AIIMS Jodhpur, 42 HZO patients, mainly <60 years (66%) and female, were analyzed. None had
varicella-zoster vaccination but all received COVID-19 vaccines. Common symptoms included maculopapular rash and eyelid edema. Initially, 72% had visual acuity <20/40, improving to >20/40 in 90% upon follow-up. Follicular conjunctivitis (90.04%) and epithelial involvement (76%) were common, with stromal keratitis (66.6%) and keratouveitis (50%) also noted. Symptoms resolved in 13 days on average, with a 9.5% recurrence rate. Main complications were post-herpetic neuralgia (71.4%), neurotrophic keratopathy (47.61%), and cataracts (42.8%), with one case of phthisis.

Conclusions

Conclusions: This investigation elucidates the clinical spectrum and demographic characteristics of HZO in a post- pandemic context, emphasizing the critical need for heightened vigilance and prompt therapeutic intervention to alleviate the burden of HZO complications.