ESCRS - PO692 - Infectious Keratitis: Risk Factors, Clinical Features And Microbiological Findings In A Tertiary Hospital.

Infectious Keratitis: Risk Factors, Clinical Features And Microbiological Findings In A Tertiary Hospital.

Published 2024 - 42nd Congress of the ESCRS

Reference: PO692 | Type: Poster | DOI: 10.82333/w9hk-x980

Authors: Alba González Corte* 1 , José Gálvez-Olortegui 2 , Manuel Alejandro Rodrigues Vera 1 , Ana Señaris González 1 , Marta Alvarez Coronado 1 , María Fernández García 1 , Begoña Baamonde 1

1Service of Ophtalmology,Hospital Universitario Central de Asturias,Oviedo,Spain, 2Service of Ophtalmology,Hospital Universitario Central de Asturias,Oviedo,Spain;Evidence Based Ophtalmology Unit (Oftalmoevidencia),Scientia Clinical and Epidemiological Research Institute,Trujillo,Peru

Purpose

To study the risk factors and clinical characteristics of infectious keratitis in our hospital, correlating it with the causative microorganisms and establishing the sensitivity and/or resistance to the most commonly used medical treatments.

Setting

Corneal infections represent a serious risk to vision and need to be treated quickly and efficiently. This study helps us to identify the risk factors in our environment, as well as the most frequent microorganisms and their sensitivities, in order to optimize the treatment of our patients.

Methods

Observational, descriptive, retrospective study of corneal scrapings performed between January 1, 2018, and April 31, 2023, in a tertiary-level hospital.

Results

Data were obtained from a total of 147 patients.The most important risk factors were: the use of contact lenses (35%), trauma (13%), previous surgery (11%) and exposure (7%). 28% of the patients had previous ocular pathology. Visual acuity improved with treatment in half of the patients, remained stable in 44% and worsened in 6%. The median duration of treatment was 37 days. Central involvement was present in 51% of the patients. 95% had epithelial defect. Other characteristics were analyzed: anterior chamber reaction, edema, melting, hypopyon, satellite lesions, etc. The scraping result was positive in 92 of the patients. A total of 102 microorganisms were isolated. Sensitivities to the most frequently used eye drops were analyzed.

Conclusions

Chronic use of contact lenses and trauma are the main risk factors for infectious keratitis in our environment. Ulceration and anterior chamber reaction were the most frequent findings. Gram-positive bacteria were the most frequently isolated germs, with Staphylococcus epidermidis standing out.