ESCRS - PO688 - Comparison Of Visual Outcomes And Tear Film Analysis After Myopic Femtosecond Laser-Assisted In Situ Keratomileusis (Fs-Lasik) Versus Fs-Lasik Combined With Prophylactic Corneal Cross-Linking

Comparison Of Visual Outcomes And Tear Film Analysis After Myopic Femtosecond Laser-Assisted In Situ Keratomileusis (Fs-Lasik) Versus Fs-Lasik Combined With Prophylactic Corneal Cross-Linking

Published 2024 - 42nd Congress of the ESCRS

Reference: PO688 | Type: Free paper | DOI: 10.82333/zgz2-jx16

Authors: Yanzheng Song* 1 , Zecheng Wang 1 , Fengju Zhang 1 , Yushan Xu 1 , Yuyan Huang 1

1Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University,Beijing,China

Purpose

To assess the visual outcomes and the tear film stability of femtosecond laser-assisted in situ keratomileusis with prophylactic cornea cross-linking (FS-LASIK Xtra) compared with conventional FS-LASIK in myopia in Chinese individuals.

Setting

In this retrospective observational study, 56 patients who underwent FS-LASIK or FS-LASIK Xtra between September 2020 and July 2023 in Beijing Tongren Hospital were enrolled. Thirty-two subjects with thinner or unregular shaped cornea were treated with FS-LASIK Xtra to avoid the potential risk of corneal ectasia.

Methods

The postoperative visual outcomes and tear film stability were analyzed at 3 months, 6 months and 1 year after surgery. The visual quality analysis system II, contrast sensitivity function, and wavefront aberrations were measured to evaluate objective visual quality. and the quality of vision (QoV) questionnaire was used to record subjective visual quality. Tear film breakup time (TBUT) and ocular surface disease index (OSDI) were applied for tear film analysis.

Results

The preoperative age (26.5 ± 4.51 vs 25.89 ± 5.28) and sphere equivalent (SE) (-6.01 ± 2.17 vs -6.79 ± 1.75) of the two groups were comparable, but the central corneal thickness (CCT) of the FS-LASIK Xtra group was significantly thinner (P = 0.001). There was no statistical differences in uncorrected visual acuity, SE and TBUT between the two groups postoperatively. The terafoil aberration of 6 mm pupil diameter was higher in FS-LASIK Xtra group (P = 0.03). Compared with the FS-LASIK group, there was a higher QoV score (P = 0.01) about glare in FS-LASIK Xtra group, which was related to preoperative SE (P=0.03) and postoperative central 2 mm epithelial thickness (P = 0.03).

Conclusions

There are comparable safety and efficiency in the visual outcomes of FS-LASIK and FS-LASIK Xtra. For young candidates with thiner and unregular shaped cornea for keratorefractive surgery, FS-LASIK Xtra procedure is a considerable treatment option.