Adapting And Applying Sub400 Protocol With Accelerated Corneal Crosslinking (Acxl) Device (9Mw /Cm2 -Continuous-Light Uv Irradiation).

To evaluate the clinical results and success rate in the treatment of Keratoconus (KC) in ultrathin Corneas with accelerated corneal crosslinking 9mW/cm2  with a follow up of 24 months based on the Sub400 protocol in ultrathin Corneas and   the photochemical Bunsen – Roscoe´s law of reciprocity. It is understood that the UV irradiation duration was changed and adapted to get the adequate energy according to each corneal stromal thickness.

Pongo Laser Vision - Eye Clinic   Prof. Dr. Vanessa C Pongo V  Education and Research Clinic, Piura -Peru. 

Thin keratoconic corneas of 23 eyes were treated with accelerated corneal crosslinking 9mW/cm2 with a follow up of 24 months based on the Sub400 protocol in ultrathin Corneas and   the photochemical Bunsen – Roscoe´s law of reciprocity. Take into account that the UV irradiation duration was changed and adapted to get the adequate total energy according to each corneal stromal thickness.

The study was retrospective, interventional case series. 23 eyes with KC and stromal thicknesses between 250 to 390 um at the time of UV irradiation were  evaluated considering the Pre and postoperative UCVA, BCVA, refraction, Scheimpflug imaging, anterior segment optical coherence tomography, Demarcation line and endothelial cell density were evaluated.

95% of eye showed stability at 24 months. Improving of UCVA, BCVA were demonstrating and not significant changes were showed about endothelial cell density .

The Adaptation of Sub400 protocol with   ACXL 9mW/cm2 was successful for halting Keratoconus progression.