Patient-Reported Outcomes Of Visual Disturbances With A Trifocal Intraocular Lens: A Meta-Analysis
Published 2024 - 42nd Congress of the ESCRS
Reference: PO617 | Type: Poster | DOI: 10.82333/dnpy-n221
Authors: Dagny Zhu 1 , Jun Zhang 2 , Mukesh Dhariwal* 2 , Erkki Soini 3 , Christian Asseburg 3 , Suyen Karki 3
1NVISION Eye Centers,Rowland Heights,United States, 2Alcon ,Fort Worth,United States, 3ESiOR Oy,Kuopio,Finland
Purpose
Diffractive trifocal IOLs are thought to provide a high rate of spectacle independence but are associated with a high incidence of visual disturbances. In this study, we pooled published evidence on patient-reported visual disturbances following bilateral implantation of a diffractive trifocal IOL (TFNTXX, AcrySof IQ PanOptix).
Setting
Literature review, global
Methods
PubMed, AAO, APACRS, APAO, ASCRS, and ESCRS congresses were searched to identify relevant studies on trifocal TFNTXX IOLs (search period: 2021-2022). Random effects meta-analysis was performed to generate summary point estimate for the rates of visual disturbances (halo, glare, and starbursts).
Results
The 11 studies extracted as a result of the review included 580 TFNTXX patients from 10 countries with follow-up from 1 to 12 months. In pooled estimates from random effects meta-analysis, 33.6%, 43.9% and 30.4% of patients with bilateral PanOptix implantation reported experiencing glare, halos and starbursts, respectively. However only a few patients experienced severe glare (2.9%), severe halos (5.4%), and severe starbursts (3.4%) and only 0.8%, 1.4% and 2.6% of patients reported “very bothersome” glare, halos or starbursts, respectively.
Conclusions
The findings of this meta-analysis showed the risk of ‘severe’ and ‘very bothersome’ visual disturbances (halos, glare, and starbursts) is ~5% and 3% respectively in patients with bilateral implantation of PanOptix IOL which could be attributed to the enlighten optical technology enabling 88% light utilization.