Estimated Visual Acuity And Clinical Validation For Three Iols Based On Wavefront Engineering Technology

The objective of this study is to evaluate the estimated visual acuity (VA) for three intraocular lenses (IOLs) based on wavefront engineering technology. The aim is to predict the clinical outcome by taking into account the in-vitro performance obtained with optical bench testing.

Innovation and Medical Science SIFI SpA, Catania, Italy

The estimated visual acuity can be used to demonstrate the uninterrupted image quality from far to near distance. In this study, the Modulation Transfer Function (MTF) spatial frequency curves were measured for several distances for four different samples: two EDOF IOLs, Mini Well and Mini Well Proxa, a monofocal parent, Mini 4 Ready, and an extended monofocal IOL, EVOLUX. For each lens, the MTF Area (MTFa) from 1 to 50 lp/mm was evaluated for several positions and the expected visual acuity was calculated with an exponential equation. The aspheric monofocal Mini 4 Ready was used as control reference.

Mini Well, Mini Well Proxa and EVOLUX IOLs registered a progressive constant estimated VA value close to 0 logMAR from 0 D up to -2,5 D, -3 D and -2 D respectively. The Mini 4 Ready IOL registered a peak for far vision at 0 D and a subsequent monotonically decreasing estimated visual acuity, as expected for an aspheric monofocal IOL. The estimated VA results demonstrated the uninterrupted extension of the depth of focus of the three IOLs based on wavefront engineering technology.

The validation of the results was carried out through comparison with the clinical data reported in literature and provided by private clinical practice. The expected visual acuity of the four samples seems to slightly overestimate the clinical visual acuity. However, the trend obtained with the optical assessment is consistent with the clinical outcome. The extension of the depth of focus is confirmed for the three IOLs based on wavefront engineering technology.