Comparison Of Clinical Outcomes After Bilateral Implantation Of Hybrid Extended Depth Of Focus (Edof)-Multifocal Intraocular Lens (Iol) And Mix-And-Match Implantation Of Edof And Hybrid Edof-Multifocal Iol

To evaluate and compare the clinical outcomes of bilateral implantation of hybrid extended depth of focus (EDOF)-multifocal intraocular lens (IOL) and mix-and-match cataract surgery using an EDOF IOL and hybrid EDOF-multifocal IOL.

Asan Medical Center, Seoul, South Korea.

Patients who underwent bilateral implantation of hybrid EDOF-multifocal IOL (Synergy, J&J) (Group 1) and who had a mix-and-match implantation of EDOF IOL (Symfony, J&J) in the dominant eye and hybrid EDOF-multifocal IOL in the non-dominant eye (Group 2) were evaluated. Uncorrected distance visual acuity (UDVA), uncorrected intermediate visual acuity (UIVA), uncorrected near visual acuity (UNVA), corrected distance visual acuity (CDVA), defocus curve, contrast sensitivity, and satisfaction questionnaire were evaluated before and at 6 months after the surgery.

70 eyes of 35 patients (9 patients in group 1 and 26 patients in group 2) were enrolled. At six months after surgery, mean UDVA was 0.10±0.05 logMAR in group 1, 0.09±0.10 logMAR in group 2. Mean UIVA was 0.04±0.05 logMAR in group 1, 0.07±0.06 logMAR in group 2. Mean UNVA was 0.32±0.22 logMAR in group 1, 0.42±0.30 logMAR in group 2 (p >0.05). Group 2 showed better contrast sensitivity at photopic, mesopic condition but showed no significant difference. The proportions of photic phenomena (glare & halo) and need for glasses were not statistically different between the two groups. Very satisfied or satisfied patients were 66.5% of group 1, while 77% in group 2.

Both groups provided an effective visual outcome. Mix-and-match implantation exhibited better distant visual acuity and more patients with satisfied visual quality. The combination of EDOF and hybrid EDOF-multifocal IOL may be a good option with comfortable vision.