ESCRS - PO504 - Predictors Of Clinically Meaningful Changes In Catquest-9Sf In A National Cataract Surgery Registry

Predictors Of Clinically Meaningful Changes In Catquest-9Sf In A National Cataract Surgery Registry

Published 2024 - 42nd Congress of the ESCRS

Reference: PO504 | Type: Free paper | DOI: 10.82333/z7zz-4w28

Authors: Miguel Raimundo* 1 , Madalena Plácido 2 , Rafael Wendel 2 , Emanuel Melo 3 , Joana Feijó 3 , Joaquim Murta 1

1Ophthalmology,ULS Coimbra,Coimbra,Portugal;Clinical Academic Center of Coimbra,Coimbra,Portugal;Faculty of Medicine of Coimbra,Coimbra,Portugal, 2Promptly Health,Porto,Portugal, 3Health Cluster Portugal,Lisbon,Portugal

Purpose

To evaluate the impact of several clinical characteristics related to cataract surgery on achieving clinically meaningful changes as evaluated by the Catquest-9SF questionnaire.

Setting

Public and private hospitals affiliated to the national portuguese cataract surgery registry (CAT.PT)

Methods

Retrospective registry-based study. Data from the CAT.PT registry consisting of cases who completed both clinician and patient reported outcomes (Catquest-9SF) evaluations were included. Catquest-9SF Rasch model was applied to the individual responses and the final score was calculated. Patients were classified in two groups according to the preoperative Catquest-9SF score and the 25th percentile cut-off (-1.50), G1 ≤ -1.50; G2 ≥ -1.49, with more negative values representing less visual-related disability. The minimum important difference (MID) was established for each group, representing a clinically meaningful change, and the odds of achieving the MID by different clinical predictors were evaluated by logistic regression analysis.

Results

We include 3530 subjects. The difference between post- and preoperative scores was 2.719, 0.856 for G1 and 3.328 for G2, representing a larger improvement in vision-related quality of life in the group with greater vision-related disability (G2). When evaluating factors associated with significantly (all p<0.050) increased odds of achieving a MID we found that larger variations in post-/preoperative visual acuity, better postoperative visual acuities, cataract surgery in the fellow eye, use of a presbyopia-correcting IOLs and the presence of surgical technical difficulty factors are associated with increased odds of achieving Catquest-9SF MID, while postoperative complications were negatively associated with achieving MID.

Conclusions

Clinical characteristics associated with significant (positive or negative) MID in Catquest 9-SF were identified in a large multicenter national cataract surgery registry. The MID methodology is promising in identifying the core drivers of clinically meaningful changes following cataract surgeries.