Steroid Response After Phacoemulsification In Patients With And Without Glaucoma
Published 2024 - 42nd Congress of the ESCRS
Reference: PO411 | Type: Poster | DOI: 10.82333/bzgd-jz35
Authors: Tatjana Sarenac Vulovic* 1 , Dusan Todorovic 2 , Nenad Petrovic 2 , Suncica Sreckovic 2 , Katarina Cupic 2 , Jovana Srejovic 2
1ophthalmology,UKC Kragujevac,Kragujevac,Serbia;Ophthalmology,Faculty of medical sciences, University of Kragujevac,Kragujevac,Serbia, 2Ophthalmology,UKC Kragujevac,Kragujevac,Serbia;Ophthalmology,Faculty of medical sciences, University of Kragujevac,Kragujevac,Serbia
Purpose
The aim of this study was to evaluate topical steroid response after uneventful phacoemlsification in patients with and without glaucoma.
Setting
Clinic of ophthalmology, University Clinical Centre, Kragujevac, Serbia.
Methods
This was a retrospective review. Patients with and without glaucoma and no prior incisional glaucoma surgery undergoing cataract surgery between February 2021and February 2024. All patients routinely received topical fixed combination of dexamethason and neomycin 4 times per day for 4 weeks postoperatively. Detailed ophtalmological examination (best-corrected visual acuity, IOP, and slit-lamp examination) was performed preoperaively, and 30th postperatively day. Steroid response was defined as intraocular pressure >50% above the baseline intraocular pressure measurement.
Results
We included 350 nonglaucoma eyes and 350 glaucoma patients. The mean age of examinated patients was 54.65 ± 10.37 years. Eleven patients (3.4%) with nonglaucoma eyes and 32 (9.2%) glaucoma eyes were diagnosed as steroid responders (relative risk=2.72; 95% confidence interval: 0.71-11.92; P<0.001). Mean preoperative IOP was 17.23 ± 3.9 mm Hg for all examiners (n = 700). Mean postoperative IOP was 22.03 ± 8.24 mm Hg in the steroid responder and 13.74 ± 3.1 mm Hg in the non-responder, with a statistically significancy in compraison with baseline IOP in the steroid responder group (p < 0.001). In nonglaucomatous group longer axial length and younger age were associated with a higher incidence of steroid response (P≤0.003).
Conclusions
The overall steroid response in this population post-cataract surgery was low, mostly in glaucomatous eyes. Risk facotrs for streoid response after phacosurgery were younger age and higher axial length. Surgeons must have those facts in their minds before and after the surgery.