ESCRS - PO286 - Repeatability And Reproducibility Of Epithelial Thickness Mapping Using A Spectral-Domain Oct

Repeatability And Reproducibility Of Epithelial Thickness Mapping Using A Spectral-Domain Oct

Published 2024 - 42nd Congress of the ESCRS

Reference: PO286 | Type: Free paper | DOI: 10.82333/y9z0-d736

Authors: Paz Paz Orts-Vila* 1 , María Ramos 1 , Cristina Tello 1 , Robert Montés-Micó 2 , Pedro Tañá-Rivero 1

1Ofalvist,Alicante,Spain, 2University of Valencia,Burjassot,Spain

Purpose

To evaluate the repeatability and reproducibility of corneal epithelial thickness measurements provided by spectral-domain optical coherence tomography (SD-OCT)

Setting

Oftalvist, Alicante, Spain

 

Methods

This prospective study was approved by the Ethics Committee of the Hospital Clínico San Carlos and registered at the DRKS German Clinical Trials Register (DRKS00032797). Inclusion criteria were age ³18 years, individuals seeking refractive surgery and no active ocular disease. Exclusion criteria were patients who had history of corneal surgery or any other significant ocular surgery, soft contact lens wear within 2 weeks before measurements, or rigid gas permeable contact lens wear within 4 weeks of measurements, patients not able to fixate and follow instructions and pregnancy or breastfeeding.

Results

These are the results of a study involving 43 eyes.  Epithelial thickness was measured in 25 sectors by two operators using the Cirrus 5000 HD-OCT.  Within-subject standard deviation (Sw), coefficient of repeatability (CoR) and coefficient of variability (CoV) were calculated to evaluate intraoperator repeatability from five consecutive measurements. Reproducibility was evaluated using a Bland-Altman analysis with the average difference, the confidence interval (CI) of the average difference at 95%, and 95% limits of agreement (LoA).

Conclusions

These preliminary outcomes reveal that  the SD-OCT provided repeatable and reproducible corneal epithelial thickness measurements