ESCRS - PO256 - Assessment Of Complications At The Graft-Host Interface Following Deep Anterior Lamellar Keratoplasty Using Anterior Segment Optical Coherence Tomography

Assessment Of Complications At The Graft-Host Interface Following Deep Anterior Lamellar Keratoplasty Using Anterior Segment Optical Coherence Tomography

Published 2024 - 42nd Congress of the ESCRS

Reference: PO256 | Type: Poster | DOI: 10.82333/5ezb-ma49

Authors: Asma Hassairi* 1 , Rim Limaiem 1 , ahmed chebil 1

1B,Institute of ophthalmology of Tunis Hedi Raeis ,TUNIS,Tunisia

Purpose

The purpose of this study is to utilize anterior segment optical coherence tomography (AS-OCT) to assess complications occurring at the graft-host interface following deep anterior lamellar keratoplasty (DALK). Specifically, we aim to investigate Descemet membrane detachments and opacities suggestive of immune or infectious interface reactions.

Setting

This retrospective study was conducted at the Institute of Ophtalmology of Tunis Hedi Raies between  January 2020 and December 2023. Patients who underwent DALK were included, and AS-OCT imaging was performed at regular postoperative intervals.

Methods

Patients who underwent DALK were included in this study. AS-OCT imaging was utilized to evaluate the graft-host interface at predetermined postoperative intervals. The presence of Descemet membrane detachments and interface opacities was assessed and correlated with clinical outcomes. 

Results

A total of 23 eyes from 23 patients were included in the analysis. AS-OCT imaging revealed Descemet membrane detachments in 17 % of cases. AS-OCT allowed for the evaluation of the extent of Descemet detachment and monitoring of reapplication after treatment. Interface opacities suggestive of immune or infectious reactions were observed in 13%  Early detection of interface opacities using AS-OCT facilitated timely intervention, preventing progression to graft rejection. 

Conclusions

AS-OCT imaging serves as a valuable tool for detecting and characterizing graft-host interface complications following DALK. Our findings highlight the importance of regular postoperative monitoring using AS-OCT to facilitate early intervention and optimize visual outcomes in patients undergoing DALK. Additionally, AS-OCT enables precise evaluation of Descemet detachment extent and facilitates effective management of interface opacities, preventing from stromal rejection.