In Vivo Imaging Of Palisades Of Vogt(Pov) Using Spectral Domain Optical Coherence Tomography(Sd-Oct) In Health And In Disease-A Case Series

 Purpose : To describe the morphology of palisades of Vogt(POV) in normal eyes and diseased state.

In a teritiery care ophthalmological hospital in Kerala

Methods: The superior and inferior limbal region of 10 normal subjects (5 males and 5 females) was assessed using spectral domain optical coherence tomography(SD-OCT).The superior and inferior limbus was divided into 3 zones and mean palisade ridge height(PRH) of 3 zones was calculated. The mean inter palisade epithelial rete peg distance(IRP) for the above mentioned 3 zones were calculated. The morphological features of 5 limbal stem cell deficiency(LSCD) patients were studied

Results: The mean PRH for superior zone a,b,c were 80.90,83.90,81 respectively. The mean PRH for inferior zone a,b,c were 93.50,82.20,81.70  respectively. The inter palisade distance (IRP) was calculated for superior zone S1,S2,S3  were 81,73.40,76.80 and inferior zone 1,2,3 were 70.70,85.10,76.80 respectively. The morphological characteristics of patients with LSCD patients was described

Conclusion: This technique of morphological analysis of palisades of Vogt will provide new insights regarding stem cell niches. In vivo SD OCT imaging is a safe and contactless modality in assessing POV