Morphologic Features Of Crystalline Lens In Extremely High Myopia And Its Correlation With The Peripheral Vault In Implantable Collamer Lens Implantation

To investigate the morphologic features of crystalline lens in extremely high myopia (EHM) and its correlation with the peripheral vaults after Implantable Collamer Lens V4c (ICL V4c; STAAR Surgical) implantation. 

Changsha Aier Eye Hospital, Changsha, China

This cross-sectional observational study included 120 consecutive eyes from 120 patients who underwent ICL implantation surgery. Eyes were divided into high myopia (HM) and EHM groups according to spherical equivalent (SE). Crystalline lens dimensional parameters were quantified using CASIA 2 swept-source anterior segment optical coherence tomography. Central vault and peripheral vault were measured 3 months after ICL implantation. Crystalline lens parameters were compared between the two groups. Spearman correlation analysis and multiple logistic regression analysis were performed to assess the relationships between the lens parameters and vault. 

Significant differences were found for peripheral vault, anterior radius of curvature (ARC), lens thickness (LT) and decentration in the HM and EHM groups (all P < 0.001). Eyes with EHM presented a lower peripheral vault, thicker LT, smaller ARC and greater decentration. LT was negatively correlated with central vault. ARC was positively correlated with central vault and peripheral vault, while decentration was found to be negatively correlated with peripheral vault (P < 0.05). 

Lens shape was closely associated with postoperative ICL vault. EHM patients with a steeper anterior curvature and a greater decentration of the crystalline lens will have lower peripheral vault.