Corneal Endothelial Cell Changes After Implantable Phakic Contact Lens (Ipcl) Versus Implantable Collamer Lens (Icl) In Myopic Patients
Published 2024 - 42nd Congress of the ESCRS
Reference: PO1186 | Type: Poster | DOI: 10.82333/d1ze-5442
Authors: Akram Fekry Elgazzar 1 , Walid Shaban Abdella 1 , Ehab Tharwat 1 , Ramy Saleh Amer* 1 , Esraa Qobeia 2 , Sanaa Ahmed Mohamed 3
1Department of Ophthalmology ,Al-Azhar university ,Damietta,Egypt, 2Al-Azhar university ,Damietta,Egypt, 3Department of Ophthalmology ,Al-Azhar university ,Cairo,Egypt
Purpose
The safety and efficacy of either implantable collamer lens (ICL) vs implantable phakic lens (IPCL) in the correction of myopia was reported, However the long-term effect of their implantation on the corneal endothelium is still a gap of knowledge. So, his study aims to assess the Corneal Endothelial Cell Changes after implantation of the implantable collamer lens (ICL) vs implantable phakic lens (IPCL) in myopic patients.
Setting
Al-Azhar university hospital, Egypt
Methods
This prospective clinical trial included 200 myopic patients who have stable refraction for at least 12 months with a dioptric power > 6 diopters attended for myopia correction. Patients were randomly divided into two groups, Group 1 (N=100) included myopic patients who were submitted for ICL implantation, and Group 2 (N=100) who were submitted for IPCL implantation. Complete ophthalmic examinations including Uncorrected Visual Acuity, Best Corrected Visual Acuity, IOP, and anterior segment examination using a Slit lamp biomicroscope were done for every patient. Specular microscopy (Specular Microscope CEM-530, NIDEK) was done for every patient at the baseline, and at 3 months, 6 months, and 12 months postoperatively
Results
The median (IQR) cell density (CD) was 2710 (2519 – 2927) cell/ mm2 in the ICL group vs 2764 (2568 – 2972 cell/ mm2 preoperativly (P =0.2). At 12 months postoperatively the CD was 2700 (2550 – 2920) cell/ mm2 in the ICL group and 2760 (2560 – 2970) cell/ mm2 in the IPCL group (P > 0.05 for both, preop. vs 12 m postop), and the difference between the two groups at 12 months postoperative was not significant statistically (P value = 0.7). As regards the coefficient of variation (CV) and cell hexagonality (HEX), we found no significant change in their values from the baseline to 12 months postoperatively in each group (P value > 0.05). Also, the two groups were relatively similar all over the follow up periods (P value = 0.6).
Conclusions
Both ICL and IPCL seem to be safe on the corneal endothelium in terms of CD, CV, and HEX.