ESCRS - PO1040 - Microcpc Vs Cyclodestructive Therapy In The Management Of Refractory Glaucoma 18 Months Follow Up

Microcpc Vs Cyclodestructive Therapy In The Management Of Refractory Glaucoma 18 Months Follow Up

Published 2024 - 42nd Congress of the ESCRS

Reference: PO1040 | Type: Free paper | DOI: 10.82333/45sf-2d79

Authors: Luis Miguel Oviedo Plathi* 1 , Nelly Rosillo 2 , Michele Petitto 3 , Jean Morales 4

1Glaucoma,IDEO,Maracaibo,Venezuela, Bolivarian Republic Of;Glaucoma,Clinica de Ojos,Maracaibo,Venezuela, Bolivarian Republic Of;Glaucoma,Hospital Universitario Maracaibo,Maracaibo,Venezuela, Bolivarian Republic Of, 2Glaucoma,IDEO,Maracaibo,Venezuela, Bolivarian Republic Of, 3Glaucoma,Clinica de Ojos,Maracaibo,Venezuela, Bolivarian Republic Of, 4Catarata & Cornea,Hospital Universitario Maracaibo,Maracaibo,Venezuela, Bolivarian Republic Of;Catarata & Cornea,Clinica de Ojos,Maracaibo,Venezuela, Bolivarian Republic Of

Purpose

To compare the effectiveness of μCPC and three cyclodestructive therapies for the management of refractory glaucoma.

 

Setting

Santa Lucia Ophthalmology Clinic & IDEO Clinic, Maracaibo, Zulia State .Venezuela 

Methods

Comparative, longitudinal, randomized study, with a sample of 80 patients with refractory glaucoma, submitted to transscleral μCPC therapy, transscleral cyclophotocoagulation, mixed treatment (µCPC+CPC) and cyclocryotherapy, the parameters evaluated were preoperative intraocular pressure, day 1, week 1, month 1, month 3 and month 6 , 1 year and 18 months; the presence of pain prior to surgery was evaluated and at month 18,  medication use at baseline and 18 months after the procedure was also evaluated, as well as the number of complications present in each group.

Results

The mean baseline IOP in all groups was 46.91 mmHg, all groups achieved a reduction in IOP at 18 months of 50 to 63% of baseline, there were statistically significant differences between the different groups (p< 0.05). All groups showed an effective reduction in pain compared to baseline (p< 0.05); Regarding the reduction in the use of drugs, the average of the groups was 3 drugs less compared to the baseline, all groups presented minor complications and rapid resolution.

 

Conclusions

All cyclodestructive techniques and μCPC are effective for the control of IOP in refractory glaucoma and pain reduction, they were also found to be effective in reducing the number of drugs used, being superior in reducing IOP with an acceptable safety profile.