Sodium Valproate Induced Cataract In An Adult
Published 2024 - 42nd Congress of the ESCRS
Reference: PO081 | Type: Case Report | DOI: 10.82333/xape-th54
Authors: Uma Yogesh Thigale* 1 , Sushank Bhalerao 1 , Pratik Gogri 2 , Sowjanya Vuyyuru 1
1Shantilal Shanghvi Cornea Institute,L V Prasad Eye Institute,Vijayawada,India, 2Cornea and Anterior Segment,Agrawal Eye Hospital,Mumbai,India
Purpose
Recent epidemiological studies confirm the prevalence of cataract in epileptic patients. Similarly, the drugs used to treat epilepsy also show the connection with increased cataract formation. We are reporting a rare case of bilateral sodium valproate induced cataract in a 21 year old man who was being treated with oral sodium valproate 500 mg daily since last 3 years for seizure disorder.
Setting
A case reported to tertiary eye care centre in South India
Report of case
A 21-year-old gentleman presented with history of diminution of vision in both eyes for one year. There was medical history of seizure disorder and drug history of oral sodium valproate (500mg) daily since last 3 years. The best corrected distance visual acuity was 20/200 in both eyes. Anterior segment examination revealed central subcapsular bread crumb like posterior subcapsular opacities with multiple radiating spoke like cortical opacities in lens of both eyes [Figure 1]. Retina examination revealed no significant findings.
It was treated with Phacoemulsification with foldable intraocular lens in right eye first and then in left eye. After 1 month of surgery, vision in both eyes was improved to 20/20 with normal intraocular pressure.
Conclusion/Take home message
Our case was a rare case of bilateral sodium valproate induced cataract which was treated with phacoemulsification with foldable intraocular lens in right eye first and then in left eye. After 1 month of surgery, vision in both eyes was improved to 20/20 with normal intraocular pressure.