ESCRS - FP31.11 - Corneal Allogenic Intrastromal Ring Segments (Cairs) & Synthetic Segments: A Comparative Analysis Using Propensity Score Matching

Corneal Allogenic Intrastromal Ring Segments (Cairs) & Synthetic Segments: A Comparative Analysis Using Propensity Score Matching

Published 2024 - 42nd Congress of the ESCRS

Reference: FP31.11 | Type: Free paper | DOI: 10.82333/xp8c-w720

Authors: Karen Asfar* 1 , Yara Bteich 1 , Jad Assaf 2 , Anthony Abou Mrad 1 , Soosan Jacob 3 , Farhad Hafezi 4 , Shady Awwad 1

1American University of Beirut Medical Center,Beirut,Lebanon, 2Casey Eye Institute, Oregon Health and Science University,Portland, Oregon,United States, 3Dr. Agarwal's Eye Hospital,Chennai,India, 4ELZA Institute and Faculty of Medicine and University of Geneva,Geneva,Switzerland

Purpose

To compare and assess the visual, refractive, and tomographic results of patients with corneal ectasia treated with either corneal allogenic intrastromal ring segments (CAIRS) or synthetic intrastromal corneal ring segments (ICRS) without concomitant corneal cross-linking.

Setting

Retrospective cohort study.

Methods

Eyes with CAIRS were matched to eyes with ICRS using the propensity score matching technique.  Each group was matched on one-to-one basis using multiple parameters such as central corneal thickness, vertical and horizontal coma, maximum anterior keratometry, steepest keratometry and age. Visual, refractive, topographic and aberrometric data were measured at baseline, 1 week, 1 month, 3 months and one year postoperatively.

Results

Preoperative parameters were similar between the 2 groups. A significant improvement at last follow-up in CDVA (0.52±0.23 to 0.16±0.18, P<0.001; 0.44±0.27 to 0.17±0.21, P<0.001), topographic astigmatism (4.45±2.75 to 3.14±1.93, P=0.001; 3.66±2.22 to 2.36±1.46, P=0.007), maximum anterior keratometry (55.85±7.53 to 50.69±6.38, P<0.001; 54.59±6.95 to 50.71±4.51, P=0.003) and vertical coma (1.49±1.02 to 0.38±0.65, P<0.001; 1.22±0.75 to 0.52±0.57, P<0.001) was observed for CAIRS and ICRS respectively. The improvements in the 2 groups were similar. No major complications were observed. One eye lost 1 CDVA line in the ICRS group. The mean thickness of the CAIRS segments at last follow up was 401.06±100.12µm, compared to 435.29±26.19µm for ICRS.

Conclusions

When adequately matched for preoperative disease type and severity, eyes with CAIRS and ICRS had a similar and notable clinical improvement.