ESCRS - FP30.08 - Retention Time Of Different Ophthalmic Viscosurgical Devices During Phacoemulsification In Rabbit Ocular Model: A Comparative Analysis.

Retention Time Of Different Ophthalmic Viscosurgical Devices During Phacoemulsification In Rabbit Ocular Model: A Comparative Analysis.

Published 2024 - 42nd Congress of the ESCRS

Reference: FP30.08 | Type: Free paper | DOI: 10.82333/cbc6-1h83

Authors: Daf Shalev* 1 , Guy Kleinmann 1

1Department of Ophthalmology,Edith Wolfson Medical Center,Holon,Israel;Faculty of Medicine,Tel Aviv University,Tel Aviv,Israel

Purpose

To compare retention times of various ophthalmic viscosurgical devices (OVDs) and soft-shell combinations. 

Setting

Laboratory setting, Rehovot, Israel.

Methods

Experimental study. Eighteen rabbit eyes were divided into six groups of three eyes, based on OVDs tested. A: Endocoat, B: HealonPro, C: Viscoat, D: Provisc, E: Endocoat and HealonPro and F: Viscoat and Provisc. OVDs were stained with 10% fluorescein dye before injected into the anterior chamber. Phacoemulsification, using fixed parameters, was performed. If OVD persisted after 60 seconds, a standardized irrigation and aspiration technique replaced phacoemulsification. The time until central and complete clearance of the OVD were video-recorded and measured for assessment. 

Results

Mean central retention times (CRT) were found to be: HealonPro - 5.33 + 2.56 seconds, Provisc - 3.33 + 1.11 seconds, Endocoat – 75.0 + 3.26 seconds, Viscoat - 62.33 + 5.19 seconds, combining HealonPro with Endocoat - 22.67 + 4.75 seconds and Provisc with Viscoat - 11.0 + 0.82 seconds. The mean total retention time (TRT) was: Endocoat – 80.0 + 8.17 seconds, Viscoat - 81.67 + 2.09 seconds, HealonPro with Endocoat - 81.33 + 3.35 seconds, and Provisc with Viscoat – 71.0 + 2.94 seconds. For HealonPro and Provisc, CRT and TRT remained identical across all trials.

Conclusions

Retention times varied, with cohesive OVDs exhibiting shorter durations than dispersive OVDs. Among dispersive OVDs, TRTs were comparable; however, Endocoat displayed an extended CRT. In soft-shell trials, the combination of HealonPro and Endocoat exhibited prolonged CRT and TRT, suggesting enhanced corneal protection.