Customized Femto- Lasik (Cfl): Raytracing Vs. Asphericity Adjustment (Cq) For Myopia And Myopic Astigmatism: 3 Month Randomized, Prospective, Contralateral Eye Study

The comparison in Safety and Efficacy of a novel automated RT optimization in customization of Excimer laser ablation vs. cQ asphericity adjustment.

Laservision Clinical and Research Institute, Athens, Greece.

This prospective randomized contralateral eye study included 50 eyes of 25 patients: 25 eyes were treated with ray tracing-optimized femto LASIK using the wavelight plus novel algorithm and the fellow eye, treated with asphericity adjustment, and refraction calculated by the ray tracing algorithm for low order aberrations only. We evaluated post-operative at 3 months: uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), refractive error, corneal keratometry, high order aberrations (HOA) and contrast sensitivity (CS) 

At the three month follow-up: Change from pre- to post-operative values at 3 months: mean refractive error -4.5 diopters (D) (range -1 to -8 D) to +0.11 ± 0.25 D; Refractive astigmatism from -1.5 ± 1.5 D (range -4 to 0 D) to -0.25 ± 0.25 D, topographic astigmatism from – 1.75 ± 1.5 D (range -4.25 to 0) to -0.33± 0.25 D.  85% vs. 45% of eyes gained one line of vision and 35% vs. 10% 2 lines respectively RT vs. cQ groups.  Although CS was comparable, HOA were statistically lower at 3 months for the RT group.

This contralateral eye study documented safe and effective femto-LASIK treatment of myopia and myopic astigmatism. The statistical significance in lines of vision gained, and induction of less HOA with raytracing automated optimization of low and HOA documents a clinical visual function advantage. Using the RT refraction appears to offer outstanding visual performance data for the asphericity adjusted group as well.