Combined Cataract Surgery With Istent Inject® Implantation Versus Cataract Surgery Alone In Patients With Open-Angle Glaucoma
Published 2024 - 42nd Congress of the ESCRS
Reference: FP03.03 | Type: Free paper | DOI: 10.82333/9qg5-hx13
Authors: Fidan Aghayeva* 1 , Otmar Ringhofer 2 , Abdelrahman Assaf 1 , Shakriiar Gurbanzade 1 , Ines Lanzl 1
1Technical University of Munich,Munich,Germany;Chiemsee Eye Clinic,Prien on Chiemsee,Germany, 2Chiemsee Eye Clinic,Prien on Chiemsee,Germany
Purpose
This study aims to evaluate and compare intraocular pressure (IOP) change and number of topical IOP-lowering medications after combined cataract surgery with iStent inject® implantation versus cataract surgery alone in patients with open-angle glaucoma.
Setting
Retrospective comparative chart review of 150 patients (150 eyes) with different types of open-angle glaucoma, who underwent combined cataract surgery with iStent® implantation or cataract surgery alone, was performed.
Methods
All the patients were naïve to any previous ocular procedure and underwent combined cataract surgery with iStent® implantation (study group - 100 patients/100 eyes) or cataract surgery alone (control group - 50 patients/50 eyes). Study outcomes were median IOP change in the operated eye and the mean number of topical IOP-lowering medications at 3, 6 and 12 months after surgery.
Results
The median pre- and postoperative IOP in the study group at 3, 6 and 12 months were 18.5 (16-20) mmHg, 14.0 (12-16.75) mmHg, 14.5 (12-16) mmHg and 14.5 (12-16) mmHg, respectively. The median IOP change in iStent® group at 3, 6 and 12 months follow up was -4 (-6 to -2) mmHg (p<0.001), -4 (-6 to -1) mmHg (p<0.001), and -4 (-6.75 to -2) mmHg (p<0.001), respectively. IOP reduction in iStent® group was statistically significantly larger than in the control group at all follow-ups (p<0.001). We found a statistically significant difference between the mean number of topical IOP-lowering medications before and at 12 months after combined surgery (1.23±0.8 vs. 1.08±0.8; p<0.001), while control group showed no reduction in preoperative medications.
Conclusions
This study shows a statistically significant IOP reduction at 3, 6 and 12 months after combined cataract surgery with iStent® implantation compared to insignificant IOP change after cataract surgery alone in glaucoma patients. iStent inject® in combination with cataract surgery is associated with the reduction of topical IOP-lowering medications at 12 months follow-up.