Relationship Between Lifestyle And The Progression Of Corneal Biomechanics In Portuguese Teenagers – A Portuguese Cohort From The Oporto Myopia Study
Published 2024 - 42nd Congress of the ESCRS
Reference: FP02.11 | Type: Free paper | DOI: 10.82333/659t-sp60
Authors: Joao Gabriel Freitas Santos* 1 , Ana Sofia Martins 1 , Joao Heitor Marques 2 , Paulo Sousa 1 , Saul Pires 1 , Renato Ambrósio 3 , Pedro Menéres 2 , João Melo Beirão 2 , Pedro Manuel Baptista 1
1Ophthalmology Department,Centro Hospitalar Universitário do Porto,Porto,Portugal, 2Ophthalmology Department,Centro Hospitalar Universitário do Porto,Porto,Portugal;Instituto de Ciências Abel Salazar,Porto,Portugal, 3Rio de Janeiro Corneal Tomography and Biomechanics Study Group ,Rio de Janeiro,Brazil
Purpose
To describe, in a cohort of Portuguese teenagers, lifestyle and the progression of corneal biomechanics, by means of Scheimpflug image, with Corvis ST (OCULUS, Germany), during a follow-up and to correlate lifestyle data with the changes in corneal biomechanical parameters over the follow-up.
Setting
Centro Hospitalar e Universitário do Porto, Porto, Portugal
Methods
This is a prospective cohort study including 126 eyes of 63 individuals. Data was collected from 2 timepoints, spaced by 2.2 (+-0.3) years. General health data and lifestyle data from the follow up interval were collected at the end of follow up, through a questionnaire. Corneal biomechanics was assessed in the baseline visit. Both 1st and 2nd generation parameters were assessed. Deltas of progression were built for the ocular biomechanics parameters. Subgroup analysis was made to address differences in biomechanical changes over the follow up, regarding different lifestyle habits. Correlations (Spearman's rank and Pearson coefficients) were addressed between ocular biomechanics deltas and the individual lifestyle variables.
Results
The present study included 126 eyes from 63 individuals, with a mean age at baseline of 14.2(+-2.6) years old.
Within the per-individual analysis, eyes from individuals with family history of myopia had lower Δ_A2 Time [ms] (0.014 VS 0.037ms, p 0.045) and lower Δ _Integrated Radius [mm^-1] (-0.644 VS -0.232, p 0.006).
Within the per-eye analysis, eyes with reported eye scratching habits had lower Δ_Radius [mm] (0.193 VS 0.432, p 0.018) and higher Δ_A2 dArc Length [mm] (0.007 VS -0.001, p 0.032).
Within the correlations analysis, weekly hours of outdoor activity were correlated with 6 biomechanical parameters, weekly hours of physical activity were correlated with 3 and daily hours spent reading/writing were correlated with 1 parameter.
Conclusions
The present study is the first report of the possible relationship between lifestyle and changes in corneal biomechanics over time in the young eye. The data presented is a step towards the possible integration of ocular biomechanics as pivotal in the integration of lifestyle habits as factors related to diseases such as corneal ectasia or myopic progression.